An unusual case of uterine leiomyoma vs. hemangiopericytoma: diagnostic dilemma solved by immunohistochemistry
Keywords:
Leiomyoma, Hemangiopericytoma, ImmunohistochemistryAbstract
Case report of a 45 year, multiparous, widow lady, who underwent total hysterectomy and bilateral salpingo-oophorectomy for uterine mass of 20 weeks. Microscopic examination revealed a hemangiopericytoma (HPC) of uterus, finally confirmed as uterine leiomyoma with cystic degeneration and HPC-like focal areas without atypia on immunohistochemical staining.
Metrics
References
Stout AP, Murray MR. Hemangiopericytoma: a vascular tumor featuring Zimmerman’s pericytes. Ann Surg.1942; 116:26-33.
Enzinger FM, Smith BH. Hemangiopericytoma. An analysis of 106 cases. Human Pathol 1976 Jan; 7(1):61-82.
Kauffmann E, Buffin RP, Dabrowski A, Delobelle-Deroide A, Lmrabet H. Uterine Hemangiopericytomas. Two case reports, J Gynecol Obstet Biol Reprod(Paris) 1995;24(2):149-54
Gengler C, Gvillou L. Review Solitary fibrous tumor and hemangiopericytoma evolution of a concept. Histopathology 2006; 48:63-74.
Deeksha P, P Priyadarshini, Mirajkar S Feroz, P S Roopa, Ranjini K, Jyothi S, Vani R. Massive degenerated leiomyomas masquerading ovarian neoplasm. Sri Lanka Journal of Obstetrics and Gynaecology2011:33; 163-165.
Subramaniam PM, Rekha PR, Thamil Selvi R. An unusual clinical and morphological features of uterine leiomyosarcoma: Immunohistochemistry solves the diagnostic pitfalls of uterine sarcomas. Journal of Clinical and Diagnostic Research [serial online] 2011 December [cited: 2013 Aug 28]; 5:1653-1655.
Rohit B, Jinru S, Amanda JH, Howard TT, Carmen T, Robert A S. Distinction of endometrial stromal sarcomas from hemangiopericytomatous tumors using a panel of immunohistochemical stains. Modern Pathology (2005)18,40-47.
Khush M, Robert S, McCluggage W.G. Application of Immunohistochemistry to Gynecologic Pathology. Arch Pathol Lab Med 2008 ; 132 :402-423.
