Induction of labour: a randomized controlled trial

Authors

  • Nivedita Reshme Department of Obstetrics and Gynecology, M. S. Ramaiah Medical College and Hospital, Bangalore, Karnataka, India
  • Rajnish Samal Department of Obstetrics and Gynecology, Bangalore Baptist Hospital, Bangalore, Karnataka, India
  • Padmaja P Department of Obstetrics and Gynecology, Bangalore Baptist Hospital, Bangalore, Karnataka, India
  • Shalini S. Department of Community Medicine, M. S. Ramaiah Medical College and Hospital, Bangalore, Karnataka, India
  • Radhika K. Department of Community Medicine, M. S. Ramaiah Medical College and Hospital, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20172342

Keywords:

Dinoprostone gel, Foley’s catheter, Induction delivery interval, Post induction, Preinduction

Abstract

ABSTRACT

Background: Clinical trial between Foley’s catheter and Dinoprostone gel for change in Bishop Score after 12 hours of labour induction, mode of delivery, maternofoetal outcome and cost effectiveness. Induction of labour is necessary if the woman does not get timely, adequate and appropriate labour pains. Bishop’s score is used to assess cervical ripening. Hence, we note the change in Bishop Score after 12 hours of labour induction to assess the success rates, time taken for active labour and delivery, maternofoetal outcome and the cost effectiveness.

Methods: Block randomized controlled clinical trial between Foley’s catheter and dinoprostone gel for a sample size of 76 in each group was done.

Results: In women administered dinoprostone gel, there was significant change in Bishop score with a mean score of 7. Shorter induction active labour interval and induction delivery interval proved it to be a faster inducing agent. No significant difference was noted in terms of mode of delivery. A higher rate of fetal distress was noted in Foley’s group probably as a result of prolonged labour and need for further augmentation with oxytocin for a long duration.

Conclusions: In terms of cost of labour Dinoprostone gel though more expensive than the Foley’s catheter, eventually proved to be equally economical for the patients considering the faster labour induction, considerable vaginal delivery rates and hence shorter stay in hospital.

References

Cunningham F, Leveno K, Bloom S, Hauth J, Rouse D, Catherine Spong,Williams text book of Obstetrics, 23rd ed: United states of America, The McGraw-Hill companies Inc;1976.

Trofatter KF, Bowers D, Gall SA, Killam AP. Pre-induction cervical ripening with prostaglandin E2 gel. Am J Obstet Gynecol. 1985;153(3):268-71.

Dewan F, Ara AM, Begum A. Foley’s catheter versus prostaglandin for induction of labour Singapore J Obstet Gynaecol 2001;32(3):56-63.

Akter S, Chowdhury SB, Fatema N. A comparison of orally administered misoprostol with vaginally administered misoprostol for cervical ripening and labour induction. ORION Med J 2010;33(1):710-3.

Stempel JE, Prins RP, Dean S. Preinduction cervical ripening: a randomized prospective comparison of the efficacy and safety of intravaginal and intracervical prostaglandin E2 gel. Am J Obstet Gynecol. 1997;176:1305-12.

Misra M, Vavre S. Induction with intracervical prostaglandin E2 gel and intravenous oxytocin in women with a very unfavourable cervix. Aust NZ J Obstet Gynecol. 1994;34:511-5.

Sorensen SS, Brocks V, Lenstrup C. Induction of labour andcervical ripening by intracervical prostaglandin E2. Obstet Gynecol. 1985;65:110-4.

Roy AC, Kottegoda SR, Ratna SS. Relaxin and reproduction. Singpore J Obstet Gynecol. 1984;15:65-9.

Naseem A, Nouman D, Iqbal J, Majeed MA, Khan MM. Intracervical Foley’s catheter balloon versus prostaglandin E2 vaginal pessary for induction of labour. J Rawalpindi Medical College (JRMC). 2007;11(2).

Dahiya K, Malik K, Dahiya A, Nanda S. Comparison of the efficacy of Foley catheter balloon with dinoprostone gel for cervical ripening at term. International J Clini Med. 2012;3(6):527.

Dalui R, Suri V, Ray P, Gupta I. Comparison of extraamniotic Foley catheter and intracervical prostaglandin E2 gel for preinduction cervical ripening. Acta obstetricia et gynecologica Scandinavica. 2005;84(4):362-7.

Deshmukh VL, Yelikar KA, Deshmukh AB. Comparative Study of Intra-cervical Foley’s Catheter and PGE2 Gel for Pre-induction Ripening (Cervical), J Obstet Gynaecol India. 2011;61(4):418-21.

Dahiya K, Malik K, Dahiya A. Comparison of the efficacy of foley catheter balloon with dinoprostone gel for cervical ripening. Int J Clini Med. 2012;3:527-31.

Sciscione AC, McCullough H, Manley JS, Shlossman PA, Pollock M, Colmorgen GH. A prospective, randomized comparison of Foley catheter insertion vs. intracervicalPGE2 gel for preinduction cervical ripening. Am J Obstet Gynecol. 1999;180:55-9.

St. Onge RD, Conners GT. Preinduction cervical ripening: a comparison of intracervical PGE2 gel vs. the Foley catheter. Am J Obstet Gynecol. 1995;172:687-90.

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Published

2017-05-25

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Original Research Articles