Study of perinatal autopsies in tertiary care hospital 20 year experience
Keywords:Intruterine, Neonatal, Perinatal, Pregnancy
Background: Losing a baby is painful. Looking for answers can help. Although nothing can change the loss, a perinatal autopsy may offer answers to better understand what happened. A perinatal autopsy is a medical exam done on the fetus or infant to help explain the cause of death. This exam may also find the underlying reason for an illness, disease or birth defect.
Methods: Babies of mothers with bad obstetrics history, died in utero, neonatal period and baby deaths of unknown cause were subjected for clinical autopsy in the last 20 years. Based on the major and associated pathological findings, an attempt was made to find the cause of death.
Results: Immaturity of the organs found to be the most common cause for perinatal death. Meconium aspiration pneumonia, external congenital abnormalities are found to be the other common causes for perinatal mortality.
Conclusions: Perinatal autopsies are the effective method of finding the cause of perinatal death, and helps to some extent in preventing the future loses.
Chiswick ML. Commentary on current World Health Organization definitions used in perinatal statistics. Br. J. Obstet. Gynec. 1986:93:1236-8.
WHO/FRH/MSM/96.7. Perinatal mortality. A listing of available information material, health and safe mother hood program. Geneva: World Health Organisations; 1996.
Dayal AK, Manning FA, Berck DJ. Fetal death after normal biophysical profile score. An 18-year experience. Am J Obstet Gynecol. 1999;181:1231-6.
Singer DB, Macpherson T. Fetal death and the macerated stillborn fetus. In. Wiggelsworth JS, Singer DB edn. Textbook of Fetal and Perinatal Pathology. Malden: Blackwell Science; 1998:246.
Arias E, MacDorman MF, Strobino DM. Annaul summary of vital statistics. 2002. Paediatrics. 2003;112:1215-30.
Bell R, Gliniania SV, Rankin J. Changing patterns of perinatal death.1982-2000: A retrospective cohort study. Arch. Dis. Child Fetal neonatal ed. 2004;89:531-6.
Bendon RW. Review of some causes of stillbirth. Paedr Der Pathol. 2001;4:517-31.
Naik V, Babu P, Reddy ES, Prasad BV, Radha BA, Myreddy N et al. Study of various congenital anomalies in fetal and neonatal autopsy. Int J Res Med Sci. 2015;3(5):1114-21.
Dandekar CP, Mysorekar VV, Rao SG, Anupama V. Perinatal Autopsy-A Six Year Study. Indian Pediatr. 1998;35:545-8.
Huang DY, Usher RH, Krammer MS. Determinants of unexplained antepartum fetal deaths. Obstet Gyenecol. 2000.95(2):215-21.
Korejo R, Bhutta S, J Noorani KJ. An audit and trends of perinatal mortality at the Jinnah Postgraduate Medical Center, Karachi. J Pak Med Assoc. 2007;57:168-72.