Uterine myxoid leiomyosarcoma: a diagnostic challenge


  • Jayalakshmi Durairaj Department of Obstetrics and Gynecology, JIPMER, Pondicherry, India
  • Swaramya Chandrasekaran Department of Obstetrics and Gynecology, JIPMER, Pondicherry, India http://orcid.org/0000-0002-7115-0263




Myxomatous degeneration, Uterine myxoid leiomyosarcoma, Uterine sarcomas


Uterine sarcomas are histologically diverse tumours which comprise about 3-7% of uterine malignancies. Myxoid leiomyosarcoma (MLMS) is an extremely uncommon variant of uterine leiomyosarcoma. This report is of a 35 year old woman who presented with urinary retention and abnormal vaginal bleeding, who underwent a total abdominal hysterectomy for cervical fibroid. A diagnosis of leiomyoma with myxomatous degeneration was made. The woman subsequently developed a recurrence within 5 months of the surgery and was diagnosed with MLMS following biopsy. This case reiterates the uncertainties associated with the diagnosis of MLMS and the need for heightened vigilance in women with myxomatous degeneration of leiomyoma.


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