Uterine myxoid leiomyosarcoma: a diagnostic challenge

Authors

  • Jayalakshmi Durairaj Department of Obstetrics and Gynecology, JIPMER, Pondicherry, India
  • Swaramya Chandrasekaran Department of Obstetrics and Gynecology, JIPMER, Pondicherry, India http://orcid.org/0000-0002-7115-0263

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20172957

Keywords:

Myxomatous degeneration, Uterine myxoid leiomyosarcoma, Uterine sarcomas

Abstract

Uterine sarcomas are histologically diverse tumours which comprise about 3-7% of uterine malignancies. Myxoid leiomyosarcoma (MLMS) is an extremely uncommon variant of uterine leiomyosarcoma. This report is of a 35 year old woman who presented with urinary retention and abnormal vaginal bleeding, who underwent a total abdominal hysterectomy for cervical fibroid. A diagnosis of leiomyoma with myxomatous degeneration was made. The woman subsequently developed a recurrence within 5 months of the surgery and was diagnosed with MLMS following biopsy. This case reiterates the uncertainties associated with the diagnosis of MLMS and the need for heightened vigilance in women with myxomatous degeneration of leiomyoma.

References

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Uterine-Sarcomas-review. Available at http://www.csh.org.tw/dr.tcj/Educartion/Cancer%20center/Uterine-Sarcomas-review.pdf

Gadducci A, Landoni F, Sartori E, Zola P, Maggino T, Lissoni A, et al. Uterine leiomyosarcoma: analysis of treatment failures and survival. Gynecol Oncol. 1996;62(1):25-32.

Leanza V, Marilli I, Genovese F, Leanza G. Uterine Myxoid Leiomyosarcoma Associated with Multiple Myomas in a Fertile Woman: A Case Report. Gynecol Obstet. 2012;2(128):2161-0932.

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Published

2017-06-24

Issue

Section

Case Reports