Takayasu’s arteritis in pregnancy: a rare case report from BJGMC and Sassoon Hospital Pune, Maharashtra, India

Amisha Dogra, Uma N. Wankhede


Takayasu’s arteritis is a chronic idiopathic vasculitis affecting aorta and its primary branches, commonly seen in young women of Asian or oriental descent during child bearing age. Incidence is 2.6 cases/million/year. It affects females in the reproductive years accounting for almost 80% of the cases. A 34 year female G2P1L1 with 9 months of amenorrhea with previous LSCS known case of takayasu arteritis, epilepsy with right side hemiparesis with aphasia. She proceeded to have elective LSCS with ventouse delivery under epidural anaesthesia and delivered alive healthy female baby weight 2.4 kg and patient was transferred to intensive care unit for observation for 48 hrs. patients intrapartum post partum period was uneventful and discharged after 1month with cardiology fitness. Pregnancy with takayasu arteritis (pulseless disease) requires a multidisciplinary management from gynaecologist, cardiologist, neurologist for favourable maternal and fetal outcome.


Pregnancy, Pulseless disease, Takayasu arteritis

Full Text:



Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002;55:481-6.

Ioscovich A, Gislason R, Fadeev A, Grisaru-Granovsky S, Halpern S. Peripartum anesthetic management of patients with takayasu’s arteritis: case series and review. Int J Obstet Anesthsiol. 2008;17:358-64.

Kathirvel S, Chavan S, Arya VK, Rehman I, Babu V, Malhotra N, Bhukal I, Chari P. Anesthetic management of patients with Takayasu’s arteritis: a case series and review. Anesth Analg. 2001;93(1):60-5.

Lupi-Herrera E, Sánchez-Torres G, Marcushamer J, Mispireta J, Horwitz S, Vela JE. Takayasu's arteritis. Clinical study of 107 cases. Am Heart j. 1977;93(1):94-103.

Matsumura A, Moriwaki R, Numano F. Pregnancy in takayasu arteritis from the view of internal medicine. Heart Vessels. 1992;7:120-4.

Domingo RT, Maramba TP, Torres LF, Wesolowski SA. Acquired aorto-arteritis: a worldwide vascular entity. Arch Surg. 1967;95:780-90.

Wilke WS. Large vessel vasculitis (giant cell arteritis, takayasu arteritis). Baillieres Clin Rheumatol. 1997;11:285-313.

Ishikawa K. Natural history and classification of occlusive thromboaortopathy (takayasu’s disease). Circulation. 1978;57:27-35.

Nabil A, Shafi MD, Amyn Malik MD, David I, Silverman MD. Management of Takayasu arteritis during pregnancy. J Clin Hypertens. 2009;11:383-5.

Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum. 1990;33:1129-34.

Vitthala S, Misra P. Takayasu’s arteritis and pregnancy: a review. The Internet J Gynecol Obstet. 2008;9(2).

Del Corso L, De Marco S, Vannini A, Pentimone F. Takayasu’s arteritis: low corticosteroid dosage and pregnancy: a case report. Angiology. 1993;44:827831.

Sharma BK, Jain S, Vasishta K. Outcome of pregnancy in Takayasu arteritis. Int J Cardiol. 2000;75 Suppl 1:S159-62.