DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20173074

Retrospective study of tumor and tumor like conditions of ovary from a rural hospital in Kerala

H. Valson, Satish Arakeri, Dally Maria Davis, Divya S.

Abstract


Background: Ovarian tumor and tumor like conditions are seen in women from early childhood to post-menopausal age. The ovaries are a pair of female sex glands responsible for the germ cell maturation, storage and release; cyclically. It also plays an important role in steroidogenesis. The ovaries are a totipotential structure and hence, neoplasms from all 3 germinal layers can be seen arising from it and manifesting clinically as ovarian tumors and tumor like conditions with its occurrence more during the late reproductive life. Ovarian tumors represent about 30% of all cancers of the female genital system. They manifesting in a wide spectrum of clinical, morphological and histological features.

Methods: This is retrospective observational study where analysis of all cases which were encountered surgically during the period Mar 2012 to Mar 2017. The cases diagnosed as ovarian tumors were subjected to thorough investigation by CA125, ultrasound (USG) abdomen and pelvis and Computerised Tomography (CT) scan. Emergency presentations with twisted cysts were operated in emergency setting and histopathological examination (HPE) done to identify the nature of tumor. IHC was done wherever necessary to sub classify and confirm the histological diagnosis. Surgeries were done either by conventional laparotomy or by laparoscopy.

Results: We have analyzed 175 cases retrospectively after histopathological diagnosis. The commonest lesions were ovarian cysts, out of which 63 cases (36%) were simple serous cyst adenomas followed by mucinous cyst adenomas 30 cases (17.14%). Germ cell tumors with struma ovarii were 34 cases (19.42%). The interesting part of the study was that we had a very high incidence of large endometriomas diagnosed as ovarian cysts before surgery 16 cases (9.4%). Two cases (1.14%) of ovarian malignancy were detected.

Conclusions: The above study has revealed a spectrum of ovarian tumors over a wide age range from adolescent to late reproductive to menopausal and late menopausal age group. The incidence of malignancy was (1.14%).


Keywords


Cystadenomas, Dermoid cysts, Endometriomas, Fibromas

Full Text:

PDF

References


Jonathan S. Berek; Berek and Novak’s Gynaecology 15th ed, Lippincott Williams & Wilkins; 2011.

Kumar P, Malhotra N. Jeffcoate’s Principles of Gynaecology. 7th ed. Jaypee Brothers Medical Publishers (P) Ltd;2008.

Parveen S, Ilyas N, Asghar S. Patterns of care for ovarian cancer: Patients at Institute of Nuclear Medicine and Oncology (INMOL) Lahore. Specialist J Pak Med Sci. 1999;15:209-15.

Murad A. Ovulation induction and ovarian tumours: the debate continues. J Pak Med Assoc. 1998;48:353-6.

TortoleroL, Mitchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer. Obstet Gynecol Clin North Am. 1994;21:63-75.

Day N.E, Krishnan E. Epidemiology of gynaecological cancers. Gynecology by Shaw R W. 2nd ed. Edinburgh: Churchill Living Stone;1997:477-87.

Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality, and clinical evaluation of 957 ovarian neoplasms: a 10-year study in a tertiary care hospital of Eastern India. J Cancer Res Ther. 2011;7(4):433-7.

Shaikh AS, Akram AI, Kamal F, Ah N. The relative frequency and histopathological pattern of ovarian masses. Biomedica 2012;28:98-102.

Hoffman B, Schorge J, Schaffer J, Halvorson L, Bradshaw K, Cunningham F. Williams Gynecology. 2 nd ed. McGraw-Hill Professional;2012.

Giurgea NL, Pitrop M, Mihailovici MS. Serous and mucinous epithelial ovarian tumors--a clinicopathologic study of 116 cases. Rev Med Chir Soc Med Nat Iasi. 2012;116(2):389-94.