Obstetrical outcome in women with congenital uterine anomalies
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20174046Keywords:
Congenital uterine anomalies, Malpresentation, Preterm birth, Small for gestational age babiesAbstract
Background: Congenital uterine anomalies are associated with higher incidence of reproductive failure and adverse obstetrical outcomes. The association of congenital anomalies and early pregnancy loss has been well established but its adverse effect on late pregnancy in from of malpresentation, preterm deliveries has not yet been elaborated. Thus, this study aims to summarize the clinical characteristics and perinatal outcome of pregnancy in women with congenital uterine anomalies.
Methods: This is a retrospective study evaluating the obstetric outcomes of 32 patients with congenital abnormalities.
Results: Among 32 women with uterine anomalies 6 delivered preterm, 16 malpresentations were seen (50%).Infants born to mothers having congenital uterine anomalies were of lower birth weight. Therefore, it can be concluded the women with congenital uterine anomalies had a higher risk of malpresentation and preterm deliveries. They also had a higher incidence of small for gestational age neonates.
Conclusions: Presence of congenital uterine anomalies has adverse effect on obstetrical outcome. This knowledge warrants the need for a larger case control study to extrapolate these findings to the general population and also to recommend the need for universal Prenatal Screening for uterine anomalies so as to improve the obstetrical outcome in patients with uterine anomalies.
References
Moore KL, Persaud TVN, Torchia MG. The urogenital system. in before we are born: essentials of embryology and birth defects. (7th edn). Saunders/Elsevier: Philadelphia, PA;2008:162-189.
Ashton D, Amin HK, Richart RM, Neuwirth RS. The incidence of asymptomatic uterine anomalies in women undergoing transcervical tubal sterilization. Obstet Gynecol. 1988;72:28-30.
Simon C, Martinez L, Pardo F, Tortajada M, Pellicer A. Mullerian defects in women with normal reproductive outcome. Fertil Steril. 1991;56:1192-3.
Acien P. Reproductive performance of women with uterine malformations. Hum Reprod 1993;8:122-6.
Jurkovic D, Gruboeck K, Tailor A, Nicolaides KH. Ultrasound screening for congenital uterine anomalies. Br J Obstet Gynecol. 1997;104:1320-1.
Raga F, Bauset C, Remohi J, Bonilla-Musoles F, Simon C, Pellicer A. Reproductive impact of congenital Mullerian anomalies. Hum Reprod. 1997;12:2277-81.
Woelfer B, Salim R, Banerjee S, Elson J, Regan L, Jurkovic D. Reproductive outcomes in women with congenital uterine anomalies detected by three-dimensional ultrasound screening. Obstet Gynecol. 2001;98:1099-1103.
Weiss A, Shalev E, Romano S. Hysteroscopy may be justified after two miscarriages. Hum Reprod. 2005;20:2628-31.
Tur-Kaspa I, Gal M, Hartman M, Hartman J, Hartman A. A prospective evaluation of uterine abnormalities by saline infusion sonohysterography in 1,009 women with infertility or abnormal uterine bleeding. Fertil Steril. 2006;86:1731-5.
Godinjak Z, Idrizbegovic E. Should diagnostic hysteroscopy be a routine procedure during diagnostic laparoscopy in infertile women? Bosn J Basic Med Sci. 2008;8:44-7.
Amesse LS, Pfaff-Amesse T. Congenital anomalies of the reproductive tract. In Clinical Reproductive Medicine and Surgery (1st edn) Falcone T, Hurd WW (eds). Mosby: New York, NY, 2007;171-190.
Ghi T, Casadio P, Kuleva M, Perrone AM, Savelli L, Giunchi S et al. Accuracy of three-dimensional ultrasound in diagnosis and classification of congenital uterine anomalies. Fertil Steril. 2009;92:808-13.
Buttram VC, Gibbons WE. Müllerian anomalies: a proposed classification (an analysis of 144 cases). Fertil Steril. 1979;32(1):40-6.
