Left ventricular dysfunction in preeclampsia: an echocardiographic study

Authors

  • Subha Sivagami Sengodan Department of Obstetrics and Gynecology, Government Mohankumarmangalam Medical College, Salem, Tamil Nadu, India
  • Mohana Dhanapal Department of Obstetrics and Gynecology, Government Mohankumarmangalam Medical College, Salem, Tamil Nadu, India
  • Anbarasi Pandian Department of Obstetrics and Gynecology, Government Mohankumarmangalam Medical College, Salem, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20174996

Keywords:

Diastolic dysfunction, Echocardiography, Preeclampsia, Systolic dysfunction

Abstract

Background: Preeclampsia is a pregnancy specific disorder which constitutes hypertension and proteinuria after 20 weeks of gestation. It is a multisystem disorder of unknown etiology. Preeclampsia is associated with significantly higher prevalence of asymptomatic global left ventricular function and myocardial injury than uneventful pregnancy. This study was undertaken to evaluate the Left ventricular changes in preeclamptic women and to compare with normotensive women.

Methods: This prospective study on left ventricular systolic and diastolic function by echocardiography was undertaken in normal and preeclamptic pregnant women who got admitted during the period of one year from January 2015 to December 2015 at Government Mohan Kumaramangalam Medical College and Hospital, Salem. Study population was divided into two groups. GROUP 1-Preeclamptic pregnant women GROUP 2-Normotensive pregnant women as control.

Results: There were significant differences in the mean end diastolic dimensions when compared to systolic dimension between two groups.

Conclusions: Women with preeclampsia have significant systolic and diastolic dysfunction compared to normotensive pregnant women. Effective management of patients who showed left ventricular dysfunction prevented pulmonaryedema and cardiac failure. This study emphasizes the importance of identifying this subset of preeclamptic patients with ECHO changes who are at higher risk of developing cardiovascular complications later in life by undergoing echocardiography.

References

Bauer ST, Clearly KL. Cardiopulmonary complications of preeclampsia. Semin Perinatol. 2009;33:158-165.

Bellamy L, Casas JP, Hingorani AD, WilliamsDJ. Pre-eclampsia and risk of cardiovascular disease disease and cancer in later in life:systematic view and meta-analysis. BMJ. 2007;335:974.

Davis EF, Lazdam M, Lewandowski AJ, Worton SA, Kelly B, Ken-worthy Y et al. Cardiovascular risk factors in children and young adults born to preeclampticpregnancies: a systematic review. Pediatrics. 2012;129:e1552-e1561.

Bauer TW, Moore GW, Hutchins GM. Morphologic evidence for coronary artery spasm in eclampsia. Circulation. 1982;65:255-9.

Melchiorre K, Sutherland GR, Liberati M, Thilaganathan B. Preeclampsia is associated with persistent postpartum cardiovascular impairment. Hypertension. 2011;58:709-715.

Jio RZ, Liu XM, Wang X, Wu HQ. Relationship between cardiovascular function and fetal growth restriction in women with pre-eclampsia. Int J Gynecol Obstet. 2010;110:61-63.

Bamfo JE, Kametas NA, Chambers JB, Nicolaides KH. Maternal cardiac function in normotensive and pre eclamptic intra uterine growth restriction. Ultra sound. Obstet Gynecol. 2008:32:682-6.

Bijnes BH, Cikes M, Claus P, Sutherland GR. Velocity and deformation imaging for the assessment of myocardial dysfunction.Eur J Echo cardiogr. 2009;10:216-226.

Rafik Hamad R, Larsson A, Pernow J, Bremme K, Eriksson MJ. Assessment of left ventricular structure and function in preeclampsia by echocardiography and cardio vascular biomarkers. J Hypertens. 2009;27:2257-64.

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Published

2017-10-28

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Section

Original Research Articles