DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20174435

A cross-sectional study on asymptomatic bacteriuria among antenatal women attending an urban tertiary health care center in Southern India

Priya Paari, Sindhuja T. P., Shanthi Dhinakaran, Christina Mary P. Paul

Abstract


Background: Asymptomatic bacteriuria (ASB) in pregnancy is a treatable risk factor for preterm delivery. India accounts for the highest preterm birth incidence in the world according to the WHO census released in November 2016. This study was aimed at finding the prevalence of asymptomatic bacteriuria, the spectrum of bacteria involved and the susceptibility pattern for the antimicrobials in the antenatal women attending a tertiary care hospital in urban Southern India.

Methods: One hundred and eighty ante-natal patients without symptoms of ongoing urinary tract infection were enrolled to this study. Clean midstream urine sample was collected in a wide mouthed container and sample was analyzed by standardized microbiological testing techniques.

Results: Out of the 180 ante-natal women included in the study, 11(6.1%) patients were found to have insignificant bacteriuria and 38(21.1%) had a significant bacteriuria. E. coli was the most frequently isolated organism and about 95% of the organisms were sensitive to Nitrofurantoin.

Conclusions: More than a fifth of all pregnant women have ASB and E. coli is the most frequent pathogen encountered.


Keywords


Antimicrobial susceptibility pattern, Asymptomatic bacteriuria, Preterm labour, Urinary tract infection

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References


Parveen K, Momen A, Begum AA. Prevalence of urinary tract infection during pregnancy. J Dhaka Natl Med Coll Hosp. 2012;17:8-12.

Ebidor UL, Tolulope A, Deborah O. Urinary tract infection amongst pregnant women in Amassoma, Southern Nigeria. Afr J Microbiol Res. 2015;9:355-9.

U. S. preventive service task force. Screening for assymptomatic bacteriuria in adults; U.S. preventive services task force reaffirmation recommendation statement. Ann intern med. 2008;149(1):43-7.

Ghafari M, Baigi V, Cheraghi Z. The prevalence of asymptomatic bacteriuria in Iranian pregnant women: a systematic review and meta-analysis. PLoS One. 2016;11:e0158031.

Jain V, Das V, Agarwal A. Asymptomatic bacteriuria and obstetric outcome following treatment in early versus late pregnancy in north Indian women. Indian J Med Res. 2013;137:753-8.

Muharram SH, Ghazali SNB, Yaakub HR. A preliminary assessment of asymptomatic bacteriuria of pregnancy in Brunei Darussalam. Malaysian J Med Sci. 2014;21:34-9.

Smaill F, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2007;(2):CD000490.

Hazhir S. Asymptomatic bacteriuria in pregnant women. Urol J. 2007;4:24-7.

Le J, Briggs GG, McKeown A. Urinary tract infections during pregnancy. Urin Tract Infect J. 2004;3:1-28.

Schnarr J, Smaill F. Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. Eur J Clin Invest. 2008;38(Suppl 2):50-7.

Patterson TF, Andriole VT. Detection, significance, and therapy of bacteriuria in pregnancy. Update in the managed health care era. Infect Dis Clin North Am. 1997;11(3):593-608.

Worthington S, Christodoulou J, Wilcken B, Peat B. Pregnancy and argininosuccinic aciduria. J Inherit Metab Dis. 1996;19(5):621-3.

Neupane MS, Dhakal KS, Neupane HC, Adhikari S, Aryal B. assymptomatic bacteruria among pregnant women attending the outpatient clinics of Chitwan medical college teaching hospital in chitwan, Nepal. IRJP. 2012;3(11):78-80.

Imade PE, Izekor PE, Egahfona NO, Enabuele OI, Ohori E. Assymptomatic bacteriuria among pregnant women. Nam J Med Sci. 2010;2(6):263-6.

Alighabi SM, Al-jaufy A, Al-moayad E. Bacterial urinary tract infection ami-ong pregnant women in Sana’a city Yemen. Arab Gulf J Sci Res. 2007;25:23-31.

Roy SK, Sinha GR, Qudros MA, A study of bacteriuria in pregnancy. J Obstet Gynecol India. 1974;24:244-51.

Demilie T, Beyene G, Melaku S, Tsegaye W. Urinary bacterial profile and antibiotic susceptibility pattern among pregnant women in North West Ethiopia. Ethiop J Health Sci. 2012;22(2):121-8.

Obirikorang C, Quaye L, Bio FY, Amidu N, Acheampong I, Addo K. Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal Clinic at the University Hospital, Kumasi, Ghana. J Med Biomed Sci. 2012;1(1):38-44.

Smail FM, Vazquez JC. Antibiotics for assymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2015;CD000490.

Assefa A, Asrat D, Woldeamanuel Y, G/Hiwot Y, Abdella A, Melesse T. Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Ethiop Med J. 2008;46:227-35.