Published: 2017-09-23

A case report: venous sinus thrombosis in pregnancy

Abhilasha Singh, Smiti Nanda


Venous sinus thrombosis (VST) should be considered in the differential diagnosis of all unexplained central nervous system disorders of sudden onset. Etiological factors are subclinical forms of several common thrombophilic states occurring together, rather than the typical inherited and rare causes. Diagnosis is often missed because of the heterogeneity in clinical presentation and radiological investigation is essential for the diagnosis. Prognosis depends on the early detection. By correcting the cause, the complications can be prevented.


Pregnancy, Thromboembolism, Thrombosis

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Bousser MG, Ferro JM. Cerebral venous thrombosis: An update. Lancet Neurol. 2007;6:162-70.

Ruiz-Sandoval JL, Chiquete E, Bañuelos-Becerra LJ, Torres-Anguiano C, González-Padilla C, Arauz A, et al. Cerebral venous thrombosis in a Mexican multicenter registry of acute cerebrovascular disease: The RENAMEVASC study. J Stroke Cerebrovasc Dis. 2012;21:395-400.

Stam J. Thrombosis of the cerebral veins and sinuses. N Eng J Med. 2005;352:1791-8.

Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35:664-70.

Coutinho JM, Ferro JM, Canhão P, Barinagarrementeria F, Cantú C, Bousser MG, et al. Cerebral venous and sinus thrombosis in women. Stroke. 2009;40(7):2356-61.

de Bruijn SF, Stam J, Koopman MM. Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users and in carriers of hereditary prothrombotic conditions. The cerebral venous sinus thrombosis study group. BMJ. 1998;316:589-92.

de Bruijn SF, de Haan RJ, Stam J. Clinical features and prognostic factors of cerebral venous sinus thrombosis in a prospective series of 59 patients for the cerebral venous sinus thrombosis study group. JNNP. 2001;70:105-8.

Schaller B, Graf R. Cerebral venous infarction: the pathophysiological concept. Cerebrovascular Dis. 2004;18(3):179-88.

Bousser MG, Chiras J, Bories J, Castaigne P. Cerebral venous thrombosis: a review of 38 cases. Stroke. 1985;16(2):199-213.

Fink JN, McAuley DL. Cerebral venous sinus thrombosis: a diagnostic challenge. Internal Med J. 2001;31:384-90.

Guenther G, Arauz A. Cerebral venous thrombosis: a diagnostic and treatment update. Neurologia. 2011;26:488-98.

Einhaupl K, Bousser MG, de Bruijn SF. EFNS guideline on the treatment of cerebral venous and sinus thrombosis. Eur J Neurol. 2006;13:553-9.