A retrospective study of 100 cases of Eclampsia: perinatal outcomes
Keywords:Eclampsia, Edema, Preeclampsia, Primigravida
Background: Eclampsia is associated with devastating maternal and foetal complications. Eclampsia is a major cause of maternal morbidity and mortality in developing countries. Evaluation of factors contributing to occurrence of eclampsia and death of eclamptic mother is of paramount importance. The aim of the study was to determine the perinatal mortality rate in eclamptic women. To assess the perinatal outcome with respect to time between first convulsion and delivery, time of treatment and delivery .To assess the perinatal outcome and mode of delivery. In this study we have tried to know the relationship between maternal blood group and eclampsia.
Methods: A retrospective study of 100 cases of eclampsia was done in P.D.U. Medical College, Rajkot. Pregnant woman diagnosed as eclampsia during this period were included. The events and outcome of mother and fetus were recorded and analyzed.
Results: Around 60% of patients were primipara and 70% patients were from rural area. On evaluation of background characteristics, 65 patients were not booked, 48% patients were hypertensive and 40% were normotensive. Out of 14 maternal deaths, five had cerebral haemorrhage, 3 had pulmonary edema, 3 had renal failure and 2 developed PPH.Conclusions: Majority of the patients were unbooked and young and primigravida. Fifteen percent of eclamptic women required cesarean delivery. Most common cause for neonatal death was prematurity and its attendant complications.
Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look PF. WHO analysis of causes of maternal death: a systematic review. Lancet. 2006;367(9516):1066- 74.
Andersgaard AB, Herbst A, Johansen M. Eclampsia in Scandinavia: incidence, substandard care, and potentially preventable cases. Acta Obstet Gynecol Scand. 2006;85(8):929-36.
Konar H, Chakraborty AB. Maternal Mortality: A FOGSI Study (Based on Institutional Data). The Journal of Obstetrics and Gynecology of India. 2013;63(2):88-95.
Patel M, Goswami K, Prajapati S, Chavda D. A five years retrospective analytic study of maternal deaths at tertiary care centre, Gujarat, India. Int J Reprod Contracept Obstet Gynecol. 2016;5:2823-7.
Abdullah A, Shaikh AA, Jamro B. Maternal and perinatal outcome associated with eclampsia in a teaching hospital, Sukkur. Rawal Medical Journal. 2010;35(1).
Waarden M, Euerle B. Pre-eclampsia (Toxaemia of pregnancy). Emer Med 2003 updated April 5 2002.
Agida ET, Adeka BI, Jibril KA. Pregnancy outcome in eclamptics at the University of Abuj Teaching Hospital, Gwagwalada, Abuja: A 3 year review. Niger J Clin Pract. 2010;13(4):394-98.
Alam IP, Akhter S. Perinatal Outcome of Eclampsia in Dhaka Medical College Hospital, Dhaka. Bangladesh J Obstet Gynaecol. 2008;23(1):20-4.
Dhananjay BS, Dayananda G, Sendilkumaran D, Murthy N. A Study of factors Affecting Perinatal Mortality in Eclampsia. JPBS. 2009;22(2):2-5.
George IO, Jeremiah I. Perinatal Outcome of Babies Delivered to Eclamptic Mothers: A Prospective Study from a Nigerian Tertiary Hospital. International Journal of Biomedical Science. 2009;5(4):390-4.
Onwuhafua PI, Oguntayo A. Perinatal mortality associated with eclampsia in Kaduna, Northern Nigeria. Niger J Med. 2006;15(4):397-400.
Kamilya G, Barracharrya SK, Mukherji J. Changing trends in the management of eclampsia from a teaching hospital. J Indian Medical Association. 2005;103(3):132,134-35.