The use of misoprostol in outpatient treatment of abortions in the first quarter of pregnancy in Dakar
Keywords:MVA, Miscarriages, Misoprostol
Background: The objective of this study was to compare the effectiveness of misoprostol comparing to MVA in support of abortion from the first quarter.
Methods: This was a prospective, descriptive and analytical study (case-control study) made between January 1st and December 31st, 2015 in a level 1 maternity in Dakar.
Results: The study included316 first trimester abortions (158 were treated with misoprostol and 158 with MVA). The epidemiological profile was a woman aged on average 28.5 years and nulliparous (37%). The mean gestational age was 8 weeks 6 days. The rate of complete uterine evacuation was comparable in both groups (93% for misoprostol versus 94.3%for MVA) with a non-significant p-value. Side effects found (40.8%) were minor. The hospital stay averaged two hours in the misoprostol group against 24 hours for MVA. Anaemia was more common in the MVA group (44.1%) than in the misoprostol group (23.6%) (p = 0.0006). The cost of treatment with misoprostol (5620 CFA francs) was on average four times less than that of MVA (21,623 CFA francs).
Conclusions: Misoprostol can be seen as a credible alternative in the management of first quarter abortions because of its many advantages including its effectiveness, its easiness to be used in ambulatory, its low cost and safety.
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