Study of clinical profile of cervical cancer patients: a hospital based study
Keywords:Cervical cancer, FIGO Staging, Lymph nodes, Wertheim’s hysterectomy
Background: As a consequence of growing and ageing populations, developing countries are disproportionately affected by the increasing number of cancers. Though the situation in India is gradually improving there still exists a disparity between the availability of quality cancer care. With this view, the present study was planned to undertake in this tertiary care institute to find out symptoms, clinical staging, complications and management of cases of carcinoma of cervix.
Methods: This was a prospective observational study of carcinoma of cervix carried out at a tertiary care hospital catering services to the people of Maharashtra and neighbouring states. A thorough history including presenting complaints, demographic details, educational status and occupational details, details of menstrual and obstetric history along with any significant past history were recorded on a standard proforma.
Results: Most common symptom was per vaginal bleeding which was found in 29 (69.04%). In the present study almost two third of cases i.e. 28 (66.6%) had advanced stage (IIB, III, IV) at the time of admission while the number of cases diagnosed at early stage were only 14 (33.3%). For Wertheim’s hysterectomy, most commonly used approach was transperitoneal 08 (61.53%) while 05 (38.46%) were operated by extraperitoneal approach. Pelvic lymph nodes were positive in 03 (23.07%).
Conclusions: A high proportion of patients presented in stages III and IV. This emphasizes the need for early detection of Gynecological cancers in our population. Accordingly, the importance of detection of the pre-clinical stage of the diseases by considering the possibility of initiating cost-effective screening measures needs to be emphasized.
Willis RA. Definition of neoplasia. Available at http://pathology.med.sumdu.edu.ua/images/stories/lecture11_t umores_1.pdf. Accessed on 12 January 2015
Senapathy JG, Umadevi P, Kannika PS. The present scenario of cervical cancer control and HPV epidemiology in India: an outline. Asian Pac J Cancer Prev. 2011 Jan 1;12(5):11.
WHO Cancer Fact Sheet N°297. Available at http://www.who.int/mediacentre/factsheets/fs297/en/ Accessed on 1 March 2015.
Aswathy S, Quereshi MA, Kurian B, Leelamoni K. Cervical cancer screening: Current knowledge andpractice among women in a rural population of Kerala, India. Indian J Med Res. 2012;136:205-210.
Denny L. Cervical Cancer treatment in Africa. Curr Opin Oncol. 2011;23(5):469-474.
Paul SB, Tiwary BK, Choudhury AP. Studies on the Epidemiology of Cervical Cancer in Southern Assam. Assam Univ J Sci Tech. 2011 Apr 6;7(1):36-42.
Shanthala S, Agadi BS, Kulkarni BB, Gai PB. Snap shot of epidemiological pattern of cervical cancer patients reporting to a tertiary cancer care center in North Karnataka, India. Int J Adva Biol Res. 2014;4(2):178-183.
Spartacus RK, Paliwal R, Gaur P, Mutha S, Bhatt Pr, Malavat A. A profile of cervical cancer cases in a government medical college hospital. IOSR-JDMS. 2015;14(10):37-42.
Yumkhaibam SD, Ramalingam M, Singh IY, Singh TT, Singh LJ, Daru HK et al. Clinicoepidemiological study of cervical carcinoma in Northeast India. Indian J Appl Res. 2016;6(8):64-66.
Swamy MN, Gomathy E, Patil S, Seema BR. The scenario of cervical cancer in a rural Medical College Hospital. Int J Pharmaceu Biomed Res. 2012;3(1):1-4
Wadhwani R, Bamnia R, Meena M. Clinico-pathological analysis of cancer cervix in tertiary care centre. J Evol Med Den Sci. 2013 Sep 30;2(39):7381-85.
Kaverappa VB, Prakash B, Kulkarni P, Renuka M. Socio-demographic profile of patients with cervical cancer in a tertiary-care cancer hospital in Mysuru, Karnataka. Int J Med Sci Public Health. 2015;4:1187-90.
Singh R, Shetty N, Naveed M, Pawar SB, Iska S, Alugubelli NR. Retrospective analysis of patients with carcinoma cervix in a rural/semi-urban setting in Western India. Indian J Med Pediatr Oncol. 2016;37:25-7.
Akhtar PS, Hossain MM, Masud ZM, Ruksana N, Nahar S, Nahar L, et al. A comparative study of result of treatment of cancer cervix patients treated by two separate schedules of radiotherapy. Bangladesh J Obstet Gynecol. 2010;25(2):50-58.
Ameen NS, Helmi ZR. The characteristics women with cervical cancer referred for radiotherapy and /or chemotherapy. Iraqi Postgraduate Med J. 2013;12(3):321-8.
Rajarao P, Hemanth Kumar B. Study of socio demographic profile of cancer cervix patients in tertiary care hospital, Karimnagar. Int J Biol Med Res. 2012;3(4):2306-10.
Berman ML, Keys H, Creasman W, DiSaia P, Bundy B, Blessing J. Survival and pattern of recurrence in cervical cancer metastatic to periaortic lymph nodes (a GOG study). Gynecol Oncol. 1984;19(1):8-16.
Stehman FB, Bundy BN, Dsaia PJ, Keys HM, Larson JE, Flower WC. Carcinoma of the cervix treated with radiation therapy: a multivariate analysis of prognostic variables in the gynecologic oncology group. Cancer. 1991;67(11):2776-85.