The relationship between lifestyle and the frequency of polycystic ovary syndrome in Saudi female residing in Riyadh

Gehan Ibrahim, Dima AlNowaiser, Howaida AlAbbasi, Joud Abuhaimed, Maha AlBukhari, Maria AlHarthi, Muneera AlSaleh, Najd AlMudaiheem, Nouf AlQahtani, Halaa Binzaid, Dania Al-Jaroudi


Background: Polycystic Ovary Disorder (PCOS) is perceived as the most widely recognized endocrinopathy in reproductive women. This study aimed to assess the relationship between the lifestyle and frequency of polycystic ovary syndrome in Saudi Arabia.

Methods: This is a case-control study conducted on females at princess Nourah University (PNU), King Fahad Medical City (KFMC) and malls in Riyadh city, Saudi Arabia. The study included females in the reproductive age including 401 controls and 122 PCOS cases.

Results: History of pregnancy related disorders was higher among the PCOS women in comparison to controls, while abortion represented the highest percentage in both cases and controls. Family history of polycystic ovary syndrome was doubled in cases than controls. There was significant increase in the percentage of hypothyroidism and hyperlipidemia in polycystic ovary syndrome patients (P <0.001). Snoring, use of oral contraceptives, high prolactin level, incidence of menorrhagia and urinary tract infection were significantly higher in cases than controls (P <0.001). In addition, there was no difference between controls and polycystic ovary syndrome cases regarding their dietary intake. On the other hand, physical activity was significantly higher in controls compared to polycystic ovary syndrome group.

Conclusions: This study supports previous studies that revealed a relation between polycystic ovary syndrome and endocrinological disorders such as hypothyroidism, hyperprolactinemia, and obesity. On the other hand, there is no relation between dietary intake and PCOS, however exercising regularly can decrease the possibility of having the disease.


Diet, Exercise, Endocrinopathy, Life style, PCOS

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Roe AH, Dokras AA. The diagnosis of polycystic ovary syndrome in adolescents. Rev Obstet Gynecol. 2011;4(2):45-51.

Pathophysiology and etiology of polycystic ovary syndrome in adolescents. 2015. Available at

Clinical evidence handbook. Polycystic ovary syndrome - American Family Physician. 2015. Available at

Guzick DS. Polycystic ovary syndrome. Obstet Gynecol. 2004;103(1):181-93.

Epidemiology and pathogenesis of the polycystic ovary syndrome in adults. 2015. Available at

Definition, clinical features and differential diagnosis of polycystic ovary syndrome in adolescents. 2015. Available at

Wright CE, Zborowski JV, Talbott EO, McHugh-Pemu K, Youk A. Dietary intake, physical activity, and obesity in women with polycystic ovary syndrome. Int J Obes Relat Metab Disord. 2004;28(8):1026-32.

Sinha U, Sinharay K, Saha S, Longkumer T, Baul S, Pal S. Thyroid disorders in polycystic ovarian syndrome subjects: a tertiary hospital based cross-sectional study from Eastern India. Indian J Endocrinol Metabol. 2013;17(2):304.

Singla R, Gupta Y, Khemani M, Aggarwal S. Thyroid disorders and polycystic ovary syndrome: an emerging relationship. Indian J Endocrinol Metabol. 2015;19(1):25.

Carmina E. Cardiovascular risk and events in polycystic ovary syndrome. Climacteric. 2009;12(1):22-5.

Wild S, Pierpoint T, Jacobs H, McKeigue P. Long-term consequences of polycystic ovary syndrome: results of a 31-year follow-up study. Hum Fertil. 2000;3(2):101-5.

Tehrani HG, Mostajeran F, Shahsavari S. The effect of calcium and vitamin D supplementation on menstrual cycle, body mass index and hyperandrogenism state of women with poly cystic ovarian syndrome. J Res Med Sci. 2014;19(9):875-80.

Wild RA, Painter PC, Coulson PB, Carruth KB, Ranney GB. Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1985;61(5):946-51.

Wild RA. Dyslipidemia in PCOS. Steroids. 2012;77(4):295-9.

Real F, Svanes C, Omenaas E, Antò J, Plana E, Janson C, et al. Menstrual irregularity and asthma and lung function. J Allergy Clin Immunol. 2007;120(3):557-64.

Filho RB, Domingues L, Naves L, Ferraz E, Alves A, Casulari LA. Polycystic ovary syndrome and hyperprolactinemia are distinct entities. Gynecol Endocrinol. 2007;23(5):267-72.

Nandalike K, Strauss T, Agarwal C, Coupey SM, Sin S, Rajpathak S, et al. Screening for sleep-disordered breathing and excessive daytime sleepiness in adolescent girls with polycystic ovarian syndrome. J Pediatr. 2011;159(4):591-6.

Mes-Krowinkel M, Louwers Y, Mulders A, de Jong F, Fauser B, Laven J. Influence of oral contraceptives on anthropomorphometric, endocrine, and metabolic profiles of anovulatory polycystic ovary syndrome patients. Fertility Sterility. 2014;101(6):1757-65.e1.

Treatment of polycystic ovary syndrome in adolescents. 2015. Available at

Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon. 2003;49(2):53-70.