Comparison of clinical outcomes in clomiphene citrate resistant infertile polycystic ovarian syndrome women after treatment with laparoscopic ovarian drilling (LOD) versus gonadotropins

Authors

  • Kumari Rupa Department of Obstetrics and Gynecology, Sir Ganga Ram Hospital, New Delhi, India
  • Kanika Jain Department of Minimal Invasive Gynecology, Institute of Obstetrics and Gynecology, Sir Ganga Ram Hospital, New Delhi, India
  • Debasis Dutta Department of Minimal Invasive Gynecology, Institute of Obstetrics and Gynecology, Sir Ganga Ram Hospital, New Delhi, India
  • Shweta Mittal Gupta Department of Obstetrics and Gynecology, Sir Ganga Ram Hospital, New Delhi, India
  • Kanika Chopra Department of Minimal Invasive Gynecology, Institute of Obstetrics and Gynecology, Sir Ganga Ram Hospital, New Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20180175

Keywords:

Gonadotropins, Infertility, Laparoscopic ovarian drilling, Polycystic ovarian syndrome

Abstract

Background: Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Objective of present study was to compare the clinical outcome of laparoscopic ovarian drilling with gonadotropin ovulation induction in patients with clomiphene resistant Polycystic Ovarian Syndrome.

Methods: Present study was a comparative interventional study conducted at the Institute of Obstetrics and Gynaecology, Sir Ganga Ram Hospital, New Delhi for a period of one and a half year. We enrolled 40 clomiphene citrate resistant infertile PCOS women who were undergoing treatment for infertility, after taking written informed consent. The women were randomly divided into two equal groups: one for LOD (laparoscopic ovarian drilling) (group A) and other for gonadotropins (group B).

Results: Out of 20, 16 women (80%) in group A ovulated with clomiphene citrate and 18 women (90%) ovulated in group B. Pregnancy was the second major outcome and 4 women (20%) in group A with clomiphene citrate got pregnant and 9 women (45%) got pregnant in group B.

Conclusions: Out of 20, 16 women (80%) in group A ovulated with clomiphene citrate and 18 women (90%) ovulated in group B. Pregnancy was the second major outcome and 4 women (20%) in group A with clomiphene citrate got pregnant and 9 women (45%) got pregnant in group B. The treatment option can be selected and tailored according to the individual needs and desires of the patient.

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Published

2018-01-23

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