Correction with oral hydration improves maternal and perinatal outcome in women with third trimester isolated oligohydramnios


  • Pragati Aggarwal Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi, India
  • Sharda Patra Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi, India



Amniotic fluid index, Isolated oligohydramnios, Oral hydration, Perinatal outcome


Background: Oligohydramnios is related to serious maternal and fetal complications. In case of isolated oligohydramnios in third trimester maternal oral hydration has shown promising results in improving maternal and perinatal outcome.

Methods: This study was conducted on 50 pregnant women complicated by idiopathic oligohydramnios (AFI<5) in third trimester. Their pre hydration daily fluid intake was noted and they were advised to take oral fluids more than their usual intake (according to their convenience). The daily fluid intake and AFI was measured on day1, day2, day3 then weekly till delivery. At delivery maternal and fetal outcome were measured.

Results: The mean AFI of the study population at the time of enrolment was 4.25±1.01 and daily mean fluid intake was 1.46±0.41. The post hydration fluid intake per day was significantly high as compared to pre hydration fluid intake (4.40±0.51 litres vs 1.46±0.41 litres, p<0.001). A significant difference in the amniotic fluid index was seen post hydration. The mean AFI on day 1, day 2, day 3 was 6.19±0.93, 7.33±1.13, 8.0±1.07 as compared to pre hydration AFI 4.25±1.01 (p<0.001). The amniotic fluid index post hydration normalized (AFI>8) in 6%, 30%, 61% and 100% of women on day1, day2, day3 and after a week. The perinatal outcome was favourable in all the women with 100% live births and a mean birth weight of 2.77±0.29 kg.

Conclusions: A simple correction of maternal dehydration by an adequate and sustained daily oral fluid intake in pregnancies complicated by isolated third oligohydramnios in third trimester significantly improves amniotic fluid index, maternal outcome and perinatal outcome.



Phelen JP, Smith CV, Broussard P, Small M. Amniotic fluid volume assessment with four quadrant technique at 36-42 weeks gestation. J Reprod Med. 1987;32:540-2.

James, Steer, Weiner, Gonik, Crowther, Robson. Abnormalities of amniotic fluid volume. High risk Pregnancy. 4th ed. Elsevier Saunders;2011:197-202.

Seth S, Mishra P, Kanti V, Shukla SK. Effect of oral hydration therapy on isolated oligohydramnios cases and perinatal outcome. J Women’s Health Issues Care. 2014;3(2):1-4.

Magann EF, Doherty DA, Chauhan SP, Barrilleaux SP, Verity LA, Martin JN. Effect of maternal hydration on amniotic fluid volume. Am J Obstetric Gynecol 2003;101(6):1261-4.

Patrelli TS, Gizzo S, Cosmi E, Carpano MG, Gangi SD, Pedrazzi G et al. Maternal hydration therapy improves the quantity of amniotic fluid and the pregnancy outcome in third-trimester isolated oligohydramnios. J Ultrasound Med. 2012;31:239-44.

Umber A. Intravenous versus oral maternal hydration therapy for increasing amniotic fluid volume. Annals. 2010;16(1):14-6.

Lorzadeh N, Kazemirad S, Lorzadeh M, Najafi S. Comparison of effect of oral and intravenous fluid therapy on women with oligohydramnios. Res J Obstet Gynecol. 2008;1(1):25-9.

Montgomery KS. An Update on Water Needs during Pregnancy and Beyond. J Perinat Edu. 2002;11(3):40-2.

EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA); Scientific Opinion on Dietary reference values for water. EFSA J. 2010;8(3):1-48.

Abbasalizadeh S, Abbasalizadeh F, Azar ZF. Effect of Desmopressin on increase of amniotic fluid volume in pregnancies with oligohydramnios. Int J Curr Res Academic Rev. 2015;3(9):227-30.

Nada Z. Oral and intravenous maternal hydration in third trimester idiopathic oligohydramnios: Effects and duration. J Nursing Health Sci. 2015;4(5):22-25.

Ahmad H, Munim S. Isolated Oligohydramnios is not an indicator for adverse perinatal outcome. JPMA. 2009;59(10):691-4.

Locateli A, vergani P, Pezzullo JC, Toso L, Verderio M. Perinatal outcome associated with oligohydramnios in uncomplicated pregnancies. Am J Obstet Gynecol. 2004;269:130-3.

Bachhav AA, Waikar M. Low amniotic fluid index at term as a predictor of adverse perinatal outcome. J Obstet Gynaecol India. 2014;64:120-3.






Original Research Articles