Effects of thrombocytopenia in pregnancy
Keywords:Antenatal visit, Fetomaternal outcome, Gestational thrombocytopenia
Background: Thrombocytopenia defined as platelet count of less than 1,50,000/cu.mm. Thrombocytopenia is divided according to severity into mild moderate and severe types. Multiple factors are responsible.
Methods: This is a retrospective study of one-year period including 120 pregnant patients irrespective of their gestational age at civil hospital Ahmedabad. Etiology of this condition are identified and analyzed.
Results: Gestational Thrombocytopenia is the most common etiology. This condition is self-limiting usually.
Conclusions: Platelet count estimation should be a routine at first antenatal visit for timely diagnosis and to achieve favorable fetomaternal outcome.
Shehata N, Burrows R, Kelton JG. Gestational thrombocytopenia. Clin Obst Gynaecol. 1999;42(2):327-34.
Burrows RF, Kelton JG. Thrombocytopenia at delivery (a prospective survey of 6,715 deliveries). Am J Obstet Gynaecol. 1990;162:731-4.
Sullivan CA, Martin JN Jr. Management of the obstetric patients with thrombocytopenia. Clin Obstet Gynecol. 1995;38:521-34.
Magann EF, Martin JN. Twelve steps to optical management of HELLP syndrome. Mississippi and Tennessee classification systems for HELLP syndrome. Clin Obstet Gynecol. 1999;42(3):532-50.
Sainio S, Kekomaki R, Rikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta Obstetr Gynecol Scand. 2000;79(9):744-9.
Levy JA, Murphy LD. Thrombocytopenia in pregnancy. JABFP. 2002;15(4):290-7.
Silver R, Berkowitz R, Bussel J. Thrombocytopenia in pregnancy. Practice bulletin, No 6. Chicago: American College of Obstetrics and Gynecology, Chicago; 1999.
Padden MO. HELLP syndrome: recognition and perinatal management. Am Fam Physician. 1999;60:829-36.
Egerman RS, Sibai BM. HELLP syndrome. Clin Obstet Gynecol. 1999;42:381-9.
Mathews JH, Benjamin S, Gill DS, Smith NA. Pregnancy associated thrombocytopenia definition, incidence and natural history. Acta Hematol. 1990;84:24-9.
Boehlen F, Hohfeld P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstet Gynecol. 2000;95(1):29-33.
Karim R, Sacher RA. Thrombocytopenia in pregnancy. Curr Hematol Resp. 2004;3(2):128-33.