DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20180901

Role of modified biophysical profile and cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies

Urvashi ., Sujani B. K., Krishna Sai Sushma

Abstract


Background: The timely detection of morbid changes in the fetal status followed by adequate interventions to avoid death or disability is one of the most important objectives of prenatal care. Objective of present study was to Comparing the role of modified biophysical profile and the cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies.

Methods: Two hundred and seventy three singleton pregnant women were included in this study. Following routine examination, amniotic fluid index, pulsatility index of middle cerebral artery and pulsatility index of umbilical artery, uterine artery mean pulsatility index were evaluated. Non stress test (NST) was done. Modified biophysical profile (MBPP) and Cerebroplacental ratio (CPR in percentile) was generated. Caeserean section because of Fetal distress, birth weight <10th centile, 5min APGAR <7, NICU stay >24hours were used in evaluating the perinatal outcome.

Results: Out of 273 cases, 107 cases had poor perinatal outcome. Out of 107 cases, 35.5% cases were IUGR, 39.2% cases underwent caesarean section in view of fetal distress, 39.2% babies had 5min APGAR <7 and 32.7% babies had stayed in NICU for >24hrs. In high risk cases, poor perinatal outcome was seen in 45.5% pregnancies and 36.7% in low risk pregnancies. Sixty seven percent of these cases had abnormal modified biophysical profile and only 7.4% cases had cerebroplacental ratio <1.

Conclusions: Modified biophysical profile was proved to be more significant than cerebroplacental ratio in prediction of perinatal outcome.

 


Keywords


Cerebroplacental ratio, Modified biophysical profile, Perinatal outcome

Full Text:

PDF

References


Mehta N, Agarwal M, Beniwal D, Sharma A, Fayyaz S. Colour Doppler versus nonstress test as prediction of adverse perinatal outcomes in high risk pregnancies. IOSR-JDMS. 2016;15(12V):79-82.

Maurya A, Kushwah N. Modified biophysical profile and fetal outcome in high risk pregnancy. Sch J App Med Sci. 2014;2(1C):283-290

Arias F, Daftary SN, Bhide AG. Practical guide to high risk pregnancy and delivery:a South Asian Perspective. 3rd ed. Elsevier India;2011:16-29.

Bhatt AB, Tank PD, Barmade KB, Damania KR. Abnormal Doppler flow velocimetry in growth retarded foetuses as a predictor of nectrotizing enterocolitis. J Postgraduate Med. 2003;48(3):145-8.

Bardakci M, Balci O, Acar A, Colacoqlu MC. Comparison of modified biophysical profile and Doppler ultrasound in predicting the perinatal outcome at or over 36 weeks of gestation. Gynecol Obstet Invest. 2010;69:245-50.

Gramellini D, Folli MC, Sacchini C, Sterbini MP, Lombardo A, Meriladi A. Fetal and maternal velocimetry in high risk pregnancies for the assessment of adverse perinatal outcome. Echocardiography. 1990;7:597-601.

Arbeille P, Carles G, Chevillot M, Locatelli A, Herve P, Perrotin F et al. Cerebral and umbilical Doppler in the prediction of fetal outcome. InDoppler Ultrasound in Obstetrics and Gynecology Springer, Berlin, Heidelberg;2005:177-197.

Turan S, Turan OM, Berg C, Mayona D, Bhide A, Bower S, et al. Computerized fetal heart rate analysis, Doppler ultrasound and biophysical profile score in the prediction of acid-base status of growth-restricted fetuses. Ultrasound Obstet Gynecol 2007;30:750-6.

DeVore GR. The importance of the cerebroplacental ratio in the evaluation of fetal well-being in SGA and AGA foetuses. Am J Obstet Gynecol. 2015;213:5-15.

Odibo AO, Riddick C, Pare E, Stamilio DM, Macones GA. Cerebroplacental Doppler ratio and adverse perinatal outcomes in intrauterine growth restriction: evaluating the impact of using gestational age-specific reference values. J Ultrasound Med. 2005 Sep;24(9):1223-8.