Placenta in pregnancy induced hypertension

Pooja Kashinath Bandekar, Prashant Bhimrao Kale


Background: Placenta is a predictor of outcome of pregnancy. Placental examination holds an important role in improving outcome of pregnancy. It is strategically located at feto-maternal interface and it acts like a record of pregnancy in which the cumulative effects of pregnancy related events and changes reflecting the intrauterine environment can be scrutinized. Objective of present study was to diagnose presence, if at all, of lesions of placenta and their nature in cases of pregnancy induced hypertension specifically in 2nd and 3rd trimester of pregnancy and to classify the lesions based on clinical presentation and to compare the results.

Methods: This study is based on histopathological examination of placenta in cases of PIH over a period of three years, from May 2011 to April 2014. The study was carried out at a tertiary care hospital.

Results: There were 280 (19.4%) cases of PIH amongst a total of 1440 cases. In these 280, 170 (60.72%) cases had severe PIH, 110 (39.28%) cases had mild PIH. Also, 180 (16.28%) cases revealed increased morbidity and mortality.

Conclusions: Evaluation of placenta is an extremely important predictor, that helps to improve the outcome of pregnancy.


Placenta, PIH, Predictor

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Narasimha Aparna, Vasudeva DS. Spectrum of changes in Placenta in toxemia of pregnancy. Indian J Pathol Microbiol 2011:54 (1): 15-20

Cunningham F, Leveno K, Bloom S, Hauth J, Rouse D, Spong C. Pregnancy Hypertension. Williams Obstetrics: 23rd Ed. United States. McGraw-Hill; 2010: Chapter 34, 706-756.

Majumdar S, Dasgupta H, Bhattacharya K, Bhattacharya A. A Study of Placenta in Normal and Hypertensive Pregnancies. J.Anat. Soc. India 2005; 54(2): 1-9

Udainia A Jain M.L Morphological Study of Placenta in Pregnancy Induced Hypertension with its Clinical Relevance. J Anat. Soc. India 2001; 50(1): 24-27.

Palaskar A and Chaudhary KR and Mayadeo, NM (2001) etoplacental weight relationship in normal pregnancy and preeclampsia-eclampsia. Bombay Hospital Journal. 43 (3): 361-3.

Thanawala U, Khopkar K. Intrauterine growth restriction, Diagnosis and management. In: Desai P, Malhotra, Shah-editors. Principles 127 and Practice of Obstetrics and gynecology. 3rd Ed. Jaypee brothers. New Delhi. 2008: 204

Mohite SS, Umarji BN, Doshi MA, Karambelkar RR. Normal Full Term Human Placenta- Morphological Study. Research Journal of Krishna Institute, Karad. 2009 July; 2 (2): 45-47.

Chakravorty, A. P. (1967): Fetal and placental weight changes in normal pregnancy and pre-eclampsia. Journal of Obstetric and Gynaecology of British Commonwealth. 74: 247-253. 130

Joshi.V. Handbook of placental pathology. New York. Igaku-Shoin Medical Pub; 1994:81-92.

Sonawane Sushilkumar. Study of Placental Pathology. In Preeclampsia EclampsiaSyndrome. [M.D.Thesis]. Karad. KIMSDU; 2003.

Kher AV, Zawar MP. Study of placental pathology in toxemia of pregnancy and itsfetal implications. Indian J PatholMicrobiol. 1981; 24: 245-51