Study of pregnancy induced hypertension in relation to placental and fetal birth weight
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20180909Keywords:
Birth weight, Fetal, Hypertension, Pregnancy, PlacentaAbstract
Background: A healthy placenta is the most important factor in producing a healthy baby. Placenta which is the most important organ for maintaining and continuing healthy pregnancy and fetal growth. Study aimed to evaluate Pregnancy induced hypertension in relation to placental and fetal birth weight.
Methods: Total 200 mothers participated in the study, various parameters related with placental and fetal weight were calculated and analysed.
Results: This study observed the reduction of placental weight in the hypertensive disorders. Placental weight shows marked variation in all the groups and coefficient of variation was higher in severe PIH group, but mean weight was less with increased severity of PIH. Baby weight shows marked variation in all the groups and coefficient of variation was increased with severity of PIH and mean weight was less with increased severity of PIH. Placental weight was significantly reduced in pre-eclamptic pregnancies and it was directly correlated with fetal birth weight.
Conclusions: Hypertensive disorders of pregnancy adversely influence the placental weight, which ultimately, adversely influence the maternal and perinatal outcomes.
References
Yetter JF. Examination of the placenta. Am Fam Phys. 1998 Mar;57(5):1045-54.
Kliman HJ. Behind every healthy baby is a healthy placenta. Parenthood Lost. Westport, CT: Bergin and Garvey. 2001:130-1.
Pijnenborg R, Bland JM, Robertson WB, Brosens I. Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. Placenta. 1983 Dec;4(4):397-413.
Goyal M, Singh KN, Agarwal R, Patel L, Khare S. Correlation of prenatal ultrasound findings with placental pathology in high risk pregnancies. JEMDS. 2014;3(3):665-72.
Adair FL, Thelander H. A study of the weight and dimensions of the human placenta in its relation to the weight of the newborn infant. Am J Obstet Gynecol. 1925;10:172-205.
Chen XK, Wen SW, Smith G, Yang Q, Walker M. Pregnancy-induced hypertension is associated with lower infant mortality in preterm singletons. BJOG. 2006;113(5):544-51.
Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J, Austalasian Society of the Study of Hypertension in Pregnancy et al. The detection, investigation and management of hypertension in pregnancy: full consensus statement. Aust N Z J Obstet Gynaecol. 2000;40(2):139-55.
Arshad A, Pasha W, Khattak TA, Kiyani RB. Impact of pregnancy induced hypertension on birth weight of newborn at term. JRMC. 2011;15(2):113-5.
Wang Y, Lewis DF, Gu Y, Zhang Y, Alexander JS, Granger DN. Placental trophoblast-derived factors diminish endothelial barrier function. J Clini Endocrinol Metab. 2004 May;89(5):2421-8.
Maqueo M, Azuela JC, Vega MDDL. Placental pathology in eclampsia and preeclampsia. Obstet Gynecol. 1964;24(3):350-5.
Das B, Dutta D, Chakraborthy S, Nath P. Placental morphology in hypertensive disorders of pregnancy and its co-relation with fetal outcome. J Obstet Gynecol India. 1996:40-6.
Udainia A, Jain ML. Morphological study of placenta in pregnancy induced hypertension with its clinical relevance. J Anat Soc India. 2001;50:24-7.
Mohan H, Sodhi S, Mohan PS, Jaiswal TS, Nagpal K, Rathee S. Fetal correlation with placental pathology in toxemia of pregnancy. J Obstet Gynecol India. 1989:170-5.
Zakowski MI, Ramanathan S. Uteroplacental circulation and Respiratory gas exchange. In Brown B, editor. Shinder and Levinson’s Anesthesia for Obstetrics, 5th ed. Lippincott William and Wikins, a Wolters Kluwer Business; 2013:18.
Salmani D, Purushothaman S, Somashekara SC, Gnanagurudasan E, Sumangaladevi K, Harikishan R et al. Study of structural changes in placenta in pregnancy-induced hypertension. J Natural Science, Biol Med. 2014 Jul; 5(2):352-5.
Singh S, Gugapriya TS. A cross sectional morphometric study of hypertensive with normal placentae and its correlation with fetal outcome. Int J Anat Res. 2014;2(2):437-42.
Raghunath G, Vijayalakshmi VS. A study on the Morphology and the Morphometry of the Human Placenta and its Clinical Relevance in a population in Tamilnadu. J Clin Diagnos Res. 2011Apr;5(2):282-6.
