Comparison of modified biophysical profile and vibroacoustic stimulation for intrapartum fetal assessment and prediction of perinatal outcome


  • Sneh Kiran Department of Obstetrics and Gynecology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
  • Abha Rani Sinha Department of Obstetrics and Gynecology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India



Intrapartum fetal assessment, Modified fetal biophysical profile, Vibroacoustic stimulation


Background: Present study was undertaken to evaluate the effectiveness and safety of intrapartum modified biophysical profile along with vibroacoustic stimulation test in the assessment of fetal well-being compared with modified biophysical profile for women with a singleton pregnancy.

Methods: This prospective study was carried out on a group of pregnant women of gestational age more than 35 weeks attending the labour room of obstetrics and gynecological department of Patna medical college and hospital, from October 2013 to October 2015. A total 220 pregnant women were selected and randomly divided into two groups, 110 women were given modified biophysical profile and 110 were underwent modified biophysical profile with VAST.

Results: Among 110 women, who underwent modified biophysical profile, 80(72.7%) showed reactive response and 30(27.3%) showed non-reactive response. A total 110 women, in whom modified biophysical profile was combined with VAST, 100(91%) showed reactive response and 10 (9%) showed non-reactive response. Statistical comparison for predicting perinatal mortality was done. Modified biophysical profile with VAST had a high sensitivity (100% vs. 80%), specificity (92.5% vs. 75.2%), negative predictive value (100% vs. 98.7%) and positive predictive value (20% vs. 13.3%) as compared to modified biophysical profile. Test accuracy for predicting perinatal mortality was more than mBPP (92.7% vs.75.4%).

Conclusions: Addition of VAST in place of NST in modified biophysical profile has high specificity & positive predictive value, shortens the testing time.


Sood AK, Singh S. Vibroacoustic stimulation and modified fetal biophysical profile for early intrapartum fetal assessment. J Obstet Gynecol India. 2011 Jun 1;61(3):291.

Tannirandorn Y, Wacharaprechanont T, Phaosavasdi S. Fetal acoustic stimulation for rapid intrapartum assessment of fetal well-being. J Med Assoc Thai. 1993;76(11):606-12.

Tongprasert F, Jinpala S, Srisupandit K, Tongsong T. The rapid biophysical profile for early intrapartum fetal wellbeing assessment. Int J Gynaecol Obstet. 2006;95(1):14-7.

Petrovic O, Frkovic A, Matejcic N. Fetal biophysical profile and vibratory acoustic stimulation in high-risk pregnancies. Int J Gynecol Obstet. 1995;50(1):11.

Manning FA. Fetal biophysical profile: a critical appraisal.Clin Obstet Gynecol. 2002;45(4):975-85.

Sarinoglu C, Dell J, Mercer BM, Sibai BM. Fetal startle response observed under ultrasonography: a good predictor of a reassuring biophysical profile. Obstet Gynecol. 1996;88:599-602.

Skupski DW, Rosenberg CR, Eglinton GS. Intrapartum fetal stimulation tests: a meta-analysis. Obstet Gynecol. 2002;99(1):129-34.






Original Research Articles