Prenatal diagnosis of a rare case of iniencephaly apertus


  • Mahy Mohsen Fetal Medicine Unit, Cairo University, Cairo, Egypt
  • Ahmed El Sheikhah Fetal Medicine Unit, Cairo University, Cairo, Egypt
  • Lamees Mohamed Fetal Medicine Unit, Cairo University, Cairo, Egypt
  • Sief El-Eslam Ali Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt
  • Armia Michael Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt
  • Ahmad A. Radwan Faculty of Medicine, Assiut University, Egypt
  • Shymaa S. Ali Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt
  • Ahmed M. Abbas Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt



Congenital malformations, Iniencephaly, Neural tube defect, Prenatal


Iniencephaly is a rare neural tube defect that was firstly reported by Saint-Hilaire in 1836. Its incidence ranges from 0.1 to 10 in 10,000 deliveries with higher incidence in females. The most common features present iniencephaly are bifida at the cervical region, defect in the occipital bone and retroflexion of the head on the cervical spine. Here we report a case of a 24 years old second gravida with a history of consanguinity. She presented with a malformed fetus at 22 weeks gestation diagnosed by detailed ultrasonographic anatomy scan as iniencephaly apparatus. Termination of pregnancy was performed vaginally through medical induction by prostaglandins.


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