DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20182355

Association of thyroid dysfunction with abnormal uterine bleeding

Lakshmi Manjeera M., Prabhneet Kaur

Abstract


Background: Abnormal uterine bleeding is a common complaint for women being referred to the gynaecologist and is associated with an array of symptoms. The objective of this study was to detect association of thyroid dysfunction in patients with menstrual irregularities

Methods: This non-interventional prospective study was done over a period of one and half years in a private medical college in Mangalore. All patients in age group of 15-55 years who presented with history of menstrual disturbances were enrolled and evaluated in the study. Patients with structural causes of AUB or using IUCDs or hormonal steroids were excluded. Total of 85 patients were hence evaluated. These 85 patients were subjected to routine investigations like Hb, BT, CT and platelets (to rule out coagulation defects) along with TSH, T3, T4 estimation. Ultrasound abdomen and pelvis with endometrial thickness was done to rule out structural causes.

Results: The most common menstrual disturbance was menorrhagia (47 patients: 55.3%). Thyroid abnormalities were found in 29 of the 85 patients with AUB (34.11%). Of the 29 patients with thyroid dysfunction, 24 were hypothyroid and 5 patients were found to be hyperthyroid.

Conclusions: Thyroid abnormalities are frequently associated with menstrual irregularities. Hence Thyroid Function Tests are extremely valuable in patients with provisional diagnosis of AUB and should be made mandatory to avoid unnecessary hormonal or surgical treatment in such patients.


Keywords


Abnormal uterine bleeding, Hyperthyroidism, Hypothyroidism, Thyroid dysfunction

Full Text:

PDF

References


Bhavani N, Avanthi S, Aradhana G, Sangeeta C, Prasannakumar VS. A study of correlation between abnormal uterine bleeding and thyroid dysfunction. Int J Recent Trends Sci Tech. 2015;14(1):131-5.

Munro MG, Critchley HOD, Fraser I. The FIGO systems for nomenclature and classification of causes of abnormal uterine bleeding in the reproductive years who needs them. Am J Obstet Gynaecol. 2012;207(4):259-65.

Fraser IS, Langham S, Uhl-Hochgraeber K. Health-related quality of life and economic burden of abnormal uterine bleeding. Expert Rev Obstet Gynecol. 2009;4(2):179-89.

Khan A, Khan MM, Akhtar S. Thyroid disorders, etiology and prevalence. J Med Sci. 2002;2(2):89-94.

Rani AS, Rekha B, Reddy GA. Study of Hypothyroidism in Women with Abnormal Uterine Bleeding. IOSR-JDMS. 2016;15:12-18.

Das A, Chugh S. Dysfunctional uterine bleeding: a clinic-pathological study. J Obstet Gynecol India. 1964;14:343-7.

Shapely M, Jordon K, Croft PR. An epidemiological survey of symptoms of menstrual loss in the community. Br J Gen Pract. 2004;54(502):359-63.

Kaur T, Aseeja V, Sharma S. Thyroid Dysfunction in dysfunctional uterine bleeding. Obstet Gynaecol. 2011;2(9):WMC002235.

Sharma N, Sharma A. Thyroid profile in menstrual disorders. J K Sci. 2012;14(1):14-7.

Deshmukh PY, Boricha BG, Pandey A. The association of thyroid disorders with abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2015;4(3):701-8.