Study of pattern of congenital anomalies at tertiary center in Maharashtra, India
Keywords:Anomalies, Consanguinity, Neonates, Prevalence
Background: To highlight common pattern of congenital malformation seen at hospital population of tertiary care center in Maharashtra.
Methods: The study was a descriptive prospective study and conducted in the department of obstetrics and gynaecology of government medical college Latur, Maharashtra for a period of six months. Study includes all womens coming for 2nd trimester MTP due to congenital anomalies in foetus and women’s admitted in labour having anomalous foetus. Details of maternal age, parity, type of anomaly present and sex of fetus were noted.
Results: Total babies born in the study period were 3482 (including the second trimester abortions). Total babies with congenital abnormality were 75, making the prevalence 2.15%. 10 cases (13.33) had multiple anomalies involving more than one system. The predominant system involved was central nervous system 40 (53.33%) followed by gastrointestinal system 15 (20%). In this study male babies affected more than females.
Conclusions: Prevalence of the congenital anomalies will be definitely higher at tertiary care center and to know prevalence in community, more community based studies are required. Increased awareness about preventable risk factors may help in reducing the incidence of congenital anomalies.
Padubidri V, Anand E, Textbook of obstetrics, BI publications Delhi; 2006:462. ISBN:81-7225-223-4.
World health organization, sixty third world health assembly, birth defects . 2010;A63:10-2.
Howson CP, Christianson AC, Modell B-Controlling birth defects: reducing the hidden toll of dying and disabled children in low-income countries. Dis Control Prior Proj. 2008.
Singh A, Gupta RK. Pattern of congenital anomalies in newborn: a hospital based prospective study. JK Sci. 2009;1:34-6.
Bhat BV, Ravikumara M. Perinatal mortality in India-Need for introspection. Indian J Matern Child Health. 1996;7:31-3.
Agarwal SS, Singh U, Singh PS, Singh SS, Das V, Sharma A, et al. Prevalence and spectrum of congenital malformations in a prospective study at a teaching hospital. Indian J Med Res. 1991;94:413-9.
Parmar A, Rathod SP, Patel SV, Patel SM. A study of congenital anomalies in newborn. NIJRM. 2010;1:13.
Chaturvedi P, Banerjee KS. Spectrum of congenital malformations in Newborns from rural Maharashtra. Indian J Pediatr. 1989;56:501-7.
Taksande A, Vilhekar K, Chaturvedi P, Jain M. Congenital malformations at birth in Central India: A rural medical college Hospital based data. Indian J Hum Genet. 2010;16(3):159-63.
Vinod SL, Balakrishnan. Pattern of congenital anomalies in a Tertiary care center. JMSCR. 2017;5:1.
Shah D. A FOGSI report on perinatal audit1999, data related to perinatal deaths from 64 centers in India, oct.95 to oct.98.
Bhat VB, Babu L.Congenital malformations at birth- A prospective study from south India. Indian J Pediatr. 1998;65:873-81.
Mohanty C, Mishra OP, Das BK, Bhatia BD, Singh G. Congenital malformations In newborns: A study of 10,874 consecutive births. J Anat Soc India. 1989;38:101-11.
Swain S, Agrawal A, Bhatia BD. Congenital malformations at birth. Indian Pediatr. 1994;31:1187-91.