A comparative study of intracervical Foley’s catheter and intracervical PGE2 gel for pre-induction cervical ripening
Keywords:Foley’s catheter, Induction of labor, PGE2gel
Background: Induction of labor is a common procedure in obstetrics. It is usually performed when risk of continuing a pregnancy is more than benefit of delivery. Cervical ripening has got a close relationship with the success rate of delivery. Although there are many methods for cervical ripening, in this study Foley’s catheter and intra-cervical PGE2 gel are compared for labor induction and cervical ripening.
Methods: This is a prospective randomized comparative study, undertaken in the department of obstetrics and gynecology, Tata Main Hospital, Jamshedpur. 70 cases in which labor was induced with Foley’s catheter were compared to other 70 cases who were induced with PGE2 gel.
Results: The commonest indication for induction in Foley’s and PGE2 gel group was pregnancy induced hypertension. There was significant increase in the post induction Bishop’s score in both the groups. The induction to delivery interval was significantly lower in Foley’s group as compared to PGE2 group (p<0.0001). Neonatal outcomes were comparable in both groups. Incidence of side effects were more in PGE2 group.
Conclusions: Foley’s catheter is safe and effective method for induction of labor compared to PGE2 gel with significant improvement in Bishop’s score and shorter induction delivery interval.
Walker S, van Rijn BB, Macklon NS, Howe DT. PLD. 31 The rising rate of labour induction: what is causing the trend?. Arch Dis Childhood-Fetal Neonatal Ed. 2014;99(Suppl 1):A115.
National Institute for Clinical Excellence. Clinical guidelines for induction of labour, Appendix-E. London: NICE; 2001.
Onge RD, Connors GT. Preinduction cervical ripening: a comparison of intracervical prostaglandin E2 gel versus the Foley catheter. Am J Obstetr Gynecol. 1995;172(2):687-90.
Embrey MP, Mollison BG. The unfavourable cervix and induction of labour using a cervical balloon. BJOG: Int J Obstetr Gynaecol. 1967;74(1):44-8.
Gu N, Ru T, Wang Z, Dai Y, Zheng M, Xu B, et al. Foley catheter for induction of labor at term: an open-label, randomized controlled trial. PloS one. 2015;10(8):e0136856.
James C, Peedicayil A, Seshadri L. Use of the Foley catheter as a cervical ripening agent prior to induction of labor. Int J Gynecol Obstet. 1994;47(3):229-32.
Dharmavijaya MN, Umashankar KM, Kavitha G, Nagpure AG, Comparative study of intra-cervical Foley’s catheter and PGE2 gel for pre-induction cervical ripening. Int J Basic and applied Med Sci. 2013;3(1): 247-53.
Laddad MM, Kshirsagar NS, Karale AV. A prospective randomized comparative study of intra-cervical Foley's catheter insertion versus PGE2 gel for pre-induction cervical ripening. Int J Reprod Contracept Obstetr Gynecol. 2016;2(2):217-20.
Sciscione AC, McCullough H, Manley JS, Shlossman PA, Pollock M, Colmorgen GH. A prospective, randomized comparison of Foley catheter insertion versus intracervical prostaglandin E2 gel for preinduction cervical ripening. Am J Obstetr Gynecol. 1999;180(1):55-9.
Deshmukh VL, Yelikar KA, Deshmukh AB. Comparative Study of Intra-cervical Foley’s Catheter and PGE 2 Gel for Pre-induction Ripening (Cervical). J Obstetr Gynecol India. 2011;61(4):418.
Revathi V, Archana I. A Comparative study of efficacy of intracervical prostaglandin E2 gel and intracervical Foley’s catheter for pre-induction cervical ripening. J Dental Med Sci (IOSR-JDMS). 2015;14(4):42-6.
Dalui R, Suri V, Ray P, Gupta I. Comparison of extraamniotic Foley catheter and intracervical prostaglandin E 2 gel for preinduction cervical ripening. Acta Obstetr Gynecol Scandinav. 2005;84(4):362-7.
Schreyer P, Sherman DJ, Ariely S, Herman A, Caspi E. Ripening the highly unfavorable cervix with extra-amniotic saline instillation or vaginal prostaglandin E2 application. Obstetr Gynecol. 1989;73(6):938-42.
Al-Taani MI. Comparison of prostaglandin E. Eastern Mediterranean Health J. 2004;10(4/5):547.
Ghezzi F, Massimo F, Raio L, Di Naro E, Balestreri D, Bolis P. Extra-amniotic Foley catheter and prostaglandin E2 gel for cervical ripening at term gestation. Eur J Obstetr Gynecol Reprod Biol. 2001;97(2):183-7.
Penaguluru R, Yaragani P, Padmaja P. comparative study of intra-cervical Foley‟s catheter and intra-cervical PGE2 gel for pre-induction ripening of cervix. Int J Contemp Med Res. 2016;3(2):410-3.