DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20183342

Study on pattern of gynaecological malignancies at Saveetha Medical College and Hospital, Tamil Nadu, India

Shanthi Ethirajan, Mohanapriya D., Aarthi C.

Abstract


Background: The burden of malignancy and deaths due to it are rising worldwide. In women gynaecological malignancies are among the most common cancers. This study was undertaken to study the pattern and relative frequencies of gynaecological malignancies among women admitted in the Department of Gynaecology, at Saveetha Medical College and Hospital, Tamil Nadu.

Methods: This is a retrospective observational study done at the department of Saveetha Medical College and Hospital over a period of two years from September 2015 to September 2017. Case records of women admitted in the Department of Gynaecology and diagnosed to have gynaecological malignancy were retrieved from the department of medical records. Information regarding demographic details, site of malignancy, histopathology of malignancy was analysed and expressed as percentages.

Results: During the study period 49 cases of gynaecological malignancies were reported. Out of 49 cases, 36 cases were cancer cervix, followed by 7 cases of ovarian malignancy and 6 cases of cancer of uterine corpus. The mean ages of cancer cervix, ovary and corpus uteri were 51.1, 53.3 and 47.2 years respectively. All women were multiparous in the study. One third of women were premenopausal. Women with cancer cervix and corpus uteri commonly presented with irregular bleeding, post-menopausal bleeding and white discharge per vaginum. Ovarian cancers presented commonly with abdominal pain and distension. Squamous cell carcinoma of cervix was the commonest histopathology seen. Adenocarcinoma and epithelial cancer was the commonest histopathology seen in endometrial and ovarian cancer respectively.

Conclusions: Cancer cervix was the commonest gynaecological malignancy in the study population followed by ovarian and uterine malignancies.


Keywords


Cervical cancer, Cancer corpus uteri, Frequency of gynaecological malignancy, Ovarian cancer

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References


Maheshwari A, Kumar N, Mahantshetty U. Gynecological cancers: a summary of published Indian data. South Asian J Cancer. 2016;5(3):112-20.

Nkyekyer K. Pattern of gynaecological cancers in Ghana. East Afr Med J. 2000;77(10):534-8.

Jamal S, Mamoon N, Mushtaq S, Luqman M, Moghal S. The pattern of gynecological malignancies in 968 cases from Pakistan. Ann Saudi Med. 2006;26(5):382-4.

Joseph A, Olisaemeka EP, Chukwudi OR, Igwe NM, Rose AM, Conrad EC. Frequency and pattern of gynaecological cancers in federal teaching hospital, Abakaliki, Nigeria. J Basic Clin Reprod Sci. 2015;4(2):54-7.

Indian Council of Medical Research. Bangalore: National Cancer Registry Programme 2007. Consolidated Report of Hospital Based Cancer Registries 2001-2003. 2007. Available at www.icmr.nic.in/ncrp/report.

Manzoor H, Naheed H, Ahmad K, Iftikhar S, Asif M, shuja J, et al. Pattern of gynaecological malignancies in south western region of Pakistan: An overview of 12 years. Biomed Rep. 2017;7:487-91.

Singh A, Kujur AV. Changing trends in genital cancer. Int J Reprod Contracept Obstet Gynecol. 2017;6(3):850-5.

Mohyuddin S, Sultana N, Butt KA, Mohyuddin A. Patterns of gynaecological malignancies at a tertiary care hospital. PJMHS. 2012;6(1):47-51.

Jeph V, Adreena, Garg PK, Mahabole K. Incidence of different malignancies in female genital tract: study in 504 women in rural population. Int J Contemp Med Res. 2017;4(1):274-86.

Agarwal S, Malhotra KP, Sinha S, Rajaram S. Profile of gynaecologic malignancies reported at a tertiary care centre in India over the past decade: Comparative evaluation with international data. Indian J Cancer. 2012;49(3):298-302.

Jhansivani Y, Rani S. Epidemiology of gynecological cancers in a tertiary care center (Government General Hospital, Guntur). IOSR J Dent Med Sci. 2015;14(9):41-5.

Seer.cancer.gov [homepage on the internet]. Bethesda, Maryland: North American Association of Central Cancer Registries; c2000. SEER Cancer statistics review 1975-2007. Available from: http:// www.seer.cancer.gov/resources.

Boyle P, Ferlay J. Cancer incidence and mortality in Europe. Ann Oncol. 2005;16:481-8.

Okeke TC, Onah N, Ikeako LC, Ezenyeaku CCT. The frequency and pattern of female genital tract malignancies at the University of Nigeria Teaching Hospital, Enugu, Nigeria. Ann Med Health Sci Res. 2013;3(3):345-8.

Junejo N, Shaikh F, Mumtaz F. Clinical presentation and treatment outcome of ovarian tumours at gynecology ward. J Liaquat University Med Health Sci. 2010;9(1):30-2.

Yakasai IA, Ugwa EA, Otubu J. Gynecological malignancies in Aminu Kano Teaching Hospital Kano: a 3-year review. Nigerian J Clin Pract. 2013;16(1):63-6.