Alveolar Rhabdomyosarcomatous endometrial polyp in a 70-year-old woman
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20183361Keywords:
Endometrial polyps, Rhabdomyosarcomatous, Sarcomatous neoplasmAbstract
TThis case report concerns a 70-year woman with a complaint of abnormal vaginal bleeding and foul smelling vaginal discharge of a short duration. Speculum examination revealed a huge polyp occupying the cervix and extending further downwards. On operation, it turned out to be an endometrial polyp arising from the fundus. Histologically the polyp showed classical features of alveolar rhabdomyosarcoma; confirmed immunochemically.
References
Garcia L, Palacios J. Pathologic and molecular features of uterine carcinosarcomas. Seminars in Diag Path. 2010;27:274-86.
Enzinger FM, Shiraki. Alveolar Rhabdomyosarcoma. An analysis of 110 cases. Cancer. 1969;14:18-31.
Parham DM, Barr FG. Alveolar Rhabdomyosarcoma in WHO classification of tumours of soft tissue and Bone. Ed by Christopher DM. Fletcher, Julia Bridge, Pancras CW, Hogendron and Fredrik Mertens Iarc;2002:130-132.
Goldblum Tr, Folpe AC, Weiss SW. Soft tissue tumors. 6th ed. Elsevier; 2013:604.
Hornick JL. Practical soft tissue Pathology. A diagnostic approach. Eds. Hornick JL. Elsevier; 2013:207.
Hosoi H, Sugimoto T, Hayashi Y, Inaba T, Horii Y, Morioka H, et al. Differential expression of myogenic regulatory genes, MyoD1 and myogenin, in human rhabdomyosarcoma sublines. Int J Canc. 1992;50(6):977-83.
Cui S, Hano H, Harada T, Takai S, Masui F, Ushigome S. Evaluation of new monoclonal anti‐MyoD1 and anti‐myogenin antibodies for the diagnosis of rhabdomyosarcoma. Pathol Int. 1999;49(1):62-8.
Fukunaga M. Pure alveolar rhabdomyosarcoma of uterine corpus. Pathol Int. 2011;61:377-81.
Case AS, Kirby TO, Conner MG, Huh WK. A case report of rhabdomyosarcoma of the uterus associated with uterine inversion. Gynecol Oncol. 2005;96(3):850-3.
Odoi AT, Dassah ET, Darkey DE, Owusu-Afriyie O, Valkov AY. Advanced alveolar rhabdomyosarcoma of the uterus: a case report. Afr J Reprod Health. 2009;13(1).