A clinico-histopathological review of ovarian masses at a tertiary care centre


  • Michelle N. Fonseca Department of Obstetrics and Gynecology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India
  • Madhavi J. Department of Obstetrics and Gynecology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India




Conservative surgery, Mucinous cystadenoma, Ovarian tumours


Background: Ovarian tumours can be seen at all stages of life but they differ in type, being mostly germ cell tumours in childhood, functional cysts in the reproductive age group (up to 45 years) and becoming increasingly malignant towards and after menopause. It also accounts for most prevalent cause of hospital admissions.

Methods: This is a retrospective study conducted in the Department of Obstetrics and Gynaecology at a tertiary care hospital in Mumbai from August 2017 to August 2018. All patients with ovarian masses who were surgically managed were included in the study. The data of 30 patients was collected in excel sheet and analyzed by descriptive statistics.

Results: Out of the 30 ovarian masses, 50 % were functional cysts, 46.6% were benign ovarian masses and 3.3% were borderline malignant. 46% of tumours were seen in the age group 21-30 years. More than 50 % tumours were seen in parous women. Most common presenting clinical symptom was pain in abdomen irrespective of the type of tumour. Most common complication was haemorrhage in the cyst. Laparoscopy was done in 4 patients and 26 required exploratory laparotomy. Most common surgery performed was unilateral cystectomy for functional ovarian cysts and benign ovarian tumours. Mucinous cystadenoma was the most common benign ovarian tumour, followed by dermoid cyst.

Conclusions: Pre-operative diagnostic approach to a patient with ovarian mass includes careful history taking, thorough clinical examination, ultrasound and tumour marker assays in selected cases. Conservative surgery should be the goal to preserve fertility in young patients with ovarian tumours.


Hassan AY, Ellatif AAA, Darweesh FF. Two-dimensional ultrasound and doppler in assessment of adnexal masses in correlation to histopathological analysis. Academic J Cancer Res. 2014;7(1):8-18.

Uma Devi K. Current status of gynaecological cancer care in India. J Gynecol Oncol. 2009;20(2):77-80.

Royal College of Obstetricians and Gynaecologists. Management of suspected ovarian masses in premenopausal women. Green-top Guideline No. 62. London: RCOG/BSGE Joint Guideline. November 2011

Berek JS, Natarajan S.Ovarian and Fallopian tube cancer. In: Berek and Novak’s Gynecology. 14th edition. New Delhi: Wolters Kluwer’s Health (India) private Limited; 2007:1447-57.

Finkler NJ, Benacerraf B, Lavin P, Wojciechowski C, Knapp RC. Comparison of serum CA 125, clinical impression, and ultrasound in the preoperative evaluation of ovarian masses. Obstet Gynecol 1988; 72(4):659-64.

Basu P, De P, Mandal S, Ray K, Biswas J. Study of ‘patterns of care’ in ovarian cancer patients in a specialized cancer institute in Kolkata, eastern India. Indian J Cancer. 2009;46(1):28-33.

Mondal SK, Banyopadhyay R, Nag DR, Roychowdhary S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India. J Can Res Ther. 2011; 7(4):433-7.

Ueland FR, Depriest PD, Desimone CP, Pavlik EJ, Lele SM, Kryscio RJ, et al. The accuracy of examination under anaesthesia and transvaginal sonography in evaluating ovarian size. Gynecol Oncol. 2005; 99(2):400-3.

Paul BJ, Lamsal B, Sinha K, Das CR. Ovarian Masses in Young Females: A Hospital based study. JNGMC. 2015;13(2):38-41.

Makwana HH, Maru AM, Lakum NR, Agnihotri AS, Trivedi NJ, Joshi JR. The relative frequency and histopathological pattern of ovarian masses-11yeaar study at tertiary care centre. Int J Med Sci Public Health. 2014;3(1):81-4.

Kanthikar SN. Clinico-Histopathological Analysis of Neoplastic Lesions of the Ovary: A 3-Year Prospective Study in Dhule, North Maharashtra, India. J Clin Diagn Res. 2014;8(8):FC04-7.

Pilli GS, Suneetha KP, Dhaded AV, Yenni W. Ovarian tumors: A study of 282 cases. J Indian Med Assoc. 2002;100(7):420-3.

Meena S, Meena RG, Jasawa A, Sabal M. A study of 60 cases of Ovarian masses at a tertiary care centre. JMSCR 2017. Volume 5(7): pp 25508-12.

Hong JH, Choi JS, Lee JH, Son CE, Jeon SW, Bae JW. Laparoscopic management of large ovarian tumors: clinical tips for overcoming common concerns. J Obstet Gynaecol Res. 2011;38(1):9-15.

Savasi I, Lacy JA, Gerstle JT, Stephens D, Kives S, Allen L. Management of ovarian dermoid cysts in the paediatric and adolescent population. J Pediatr Adolesc Gynecol 2009; 22(6):360–364.

Ben-Ami I, Smorgick N, Tovbin J, Fuchs N, Halperin R, Pansky M. Does intraoperative spillage of benign ovarian mucinous cystadenoma increase its recurrence rate? Am J Obstet Gynecol 2010; 202(142):e141-5.






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