Effects of advanced maternal age on pregnancy outcome
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20183870Keywords:
Advanced maternal age, Elderly gravida, Maternal and perinatal outcome, Preterm deliveriesAbstract
Background: Advanced maternal age, generally signify age after 35 years at the time of delivery. It is associated with decreased fertility and increased risk.
Methods: This was a prospective study conducted in Kamla Raja Hospital, G.R. Medical College, Gwalior (M.P.) during the period of one year from July 2015 to June 2016. Pregnant women aged 35 years and older at the time of delivery were selected and analyzed for maternal and perinatal outcome.
Results: A total no. of 288 elderly pregnant patients were selected for the study. Most of the cases were in the age group 35 to 39 years (89.93%). Multi gravida (71.8%) and grand multi para (22.22%) constituted the largest group. Most of the cases belong to lower socio-economic status (90%). Percentage of unbooked cases was 82.98%. The causes of delay in pregnancy were preference for male child (23.95%) and unwareness of contraception (21.52%). The incidence of diabetes mellitus and chronic hypertension were increased. Overall cesarean rate was increased (35%). Incidence of abortions 28(9.72%), preterm delivery 18(6.25%), oligohydramnios 18(6.25%), APH 18(6.25%) and PROM 17(5.90%), low birth weight baby 30(13.19%), NICU admission 20 (6.94%), IUGR 11(3.81%) all were high. The preference for male child 69(23.95%) and lack of awareness 62(21.52%) were two major reason for continuing pregnancies and deliveries till late age.
Conclusions: The present study showed that pregnancy at advanced age is a higher risk pregnancy in term of increased maternal and perinatal morbidity and mortality.
Metrics
References
Laxmy R, Beena G. Pregnancy outcome in women of advanced maternal age. Int J Bioassays. 2013;2(9):1193-8.
Bianco A, Stone J, Lynch L, Lapinski R, Berkwiutz G, Berkowitz RL. Pregnancy outcomes at age 40 and older. Obstet Gynecol. 1996;87(6):917-22.
Chloe Zera, Ruth C. Fretts. Pregnancy and advanced maternal age. Progr Obstet Gynecol. 2007;17:113-24.
Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, et al. Impact of maternal age on obstetric outcome. Obstet Gynecol 2005;;105(5):983-90.
Hoque ME. Advanced maternal age and outcomes of pregnancy: A retrospective study from South Africa. Bio Med Res 2012;23(2):281-5.
A Giri,1 VR Srivastav,1 A Suwal1 and AS Tuladhar290Advanced maternal age and obstetric outcome Med Coll J. 2012;15(2): 87
Priyadatt D Patel, Shital T Mehta, Babu S. Patel Advanced maternal age; facts, factors and fetomaternal outcome. Int J Sci Res.2016;5(1):2277-8179.
Najah Abdul Rehman, Archana Vikram, Najma Palakki, Nada Chettian Kandy. Maternal and fetal outcome in advanced maternal age. J of Evolution of Med and Dent Sci. 2015;4(6):2278-4748.
Khalil A, Yngelaki A, Maiz N, Zinevich Y, Nicoladies KH. Maternal age and adverse pregnancy outcome: a cohort study. Ultrasound Obstet Gynecol 2013;42(6):634-43
Benil AR, Benli NC, Usta AT, Atakul T, Koroglu M. Effect of maternal age on pregnancy outcome and cesarean delivery rate. J Clin Med Res. Feb 2015;7(2):97-102.
Sahu TM, Agarwal A, Das V. Advanced maternal age and obstetric outcome. J Obstet Gynecol India 2007;57(4):320-3.
Seoud M, Nassar A, Usta I, Melhem Z, Kazma A, Khalil A. Impact of advanced maternal age on pregnancy outcome. Am J Perinatol. 2002;19(1):1-7.
Pawde AA, Kulkarni MP, Unni J. Pregnancy in women aged 35 years and above: A prospective observational study. J Obstet Gynecol India. 2015;65(2):93-6.
Bayrampour H, Heaman M. Advanced maternal age and the risk of caesarean birth: a systematic review. Birth. 2010; 37(3):219.
Main DM, Main EK, Moore DH 2nd. The relationship between maternal age and uterine dysfunction: a continuous effect throughout reproductive life. Am J Obstet Gynecol 2000; 182(6):1312.
Greenberg MB, Cheng YW, Sullivan M, et al. Does length of labour vary by maternal age? Am j obstet gynecol 2007; 197(4):428.e1.
Treacy A, Robson M, O’Herlihy C. Dystocia increases with advancing maternal age. Am J Obstet Gynecol 2006;195(3):760-3
Ramachandran N, Sethuraman D, Nachimuthu V, Natrajan T. Obstetric and perinatal outcome of elderly mothers aged 35 years and above: a comparative study. Int J Res Med Sci. 2015;3(1):214-9.
National Center for Health Statistics. Birth rate for women aged 15-44.
Centers for Disease Control. Assisted Reproductive Technology (ART) Report2002 National Summary (Accessed 5/5/05).
Tietze C. Reproductive span and rate of reproduction among Hutterite women. Fertil Steril 1957;12(5): 89-97
Leeks KS, Ferguson RM, Corpuz M et al. Maternal age and incidence of low birth weight at term: a population study. Am J Obstet Gynecol 1988;158(1):84-9.
Amarin VN, Akasheh HF. Advanced maternal age and pregnancy outcome. East Mediterr Health J. 2001;7(4-5):646-51.
Nagarwal K, Chandrakanta GK, Manohar RK. Pregnancy outcome comparison in elderly and non-elderly primigravida. Int Multispeciality Journal Health. 2015;1(1):24-30.