Epidemiological, clinical and therapeutic profile of uterine fibroids at the Befelatanana University hospital centre of obstetric gynecology of Antananarivo, Madagascar

Rainibarijaona L. N. A., Randriamahavonjy R., Rakotonirina Andriamaro M., Ratsiatosika Andriamanetsiarivo T., Housni Ibrahim, Rasoanandrianina Bienvenue Solange, Hery Rakotovao Andrianampanalalinarivo


Background: Leiomyomas or fibromyomas more commonly referred as uterine fibroids are the most common tumors of the female genital tract. They affect 20 to 25% of women in genital activity. The objective of present study is to describe the epidemiological and therapeutic profile of uterine fibroids at the UHCOBG.

Methods: Retrospective and descriptive cross-sectional study of patients with uterine fibroids hospitalized in the department of gynecology of the UHCOBG between January 2015 and December 2016.

Results: In total, 101 cases of uterine fibroids have been identified with a prevalence of 3.92%. The average age is 42.75±3.6 years old. The most affected age group varies from 35 to 45 years old. Thirty-eight-point six percent of the patients were pauciparous. The medical history of irregular menstrual cycle disorders was present in 17.8% of the cases. The symptomatology was dominated by menometrorrhagia (78.2%) and in 67.3% of the cases, patients had anemia. The majority of patients (64.4%) had poly-myomatous uterus which fibroid location was predominantly corporeal (92.1%), isthmic (21.8%), and three quarters of the mapping was interstitial. Complications were dominated by aseptic necrobiosis (7.9%) and conservative treatment in 68.3% of the cases. Laparotomy is the pillar of a surgical treatment. The duration of hospitalization was short in 77.2% of the cases, 91.1% had a good progress and no death was noticed during 2 years.

Conclusions: This is the first operative indication of all gynecological pathologies in present UHC and proves to be a real public health problem. The development of operative laparoscopy is necessary to reduce the morbidity associated with treatment.


Fibroids, Laparotomy, Metrorrhagia

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