Acute renal failure in preeclampsia and eclampsia
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20184974Keywords:
Acute renal failure, Eclampsia, PreeclampsiaAbstract
Background: Incidence of acute renal failure (ARF) in preeclampsia and eclampsia is reported to be alarmingly high. Present study was conducted to evaluate the incidence of acute renal failure (ARF) in our institute, to study ARF associated risk factors and its complications along with pregnancy outcome evaluation.
Methods: All 812 patients of preeclampsia and eclampsia admitted in the department of obstetrics and gynecology during the study period at our institute were studied. Out of them, the 44 patients diagnosed with ARF were analyzed in detail in terms of maternal age, gravida, booked/unbooked, gestational age, associated complications, management and outcome of pregnancy.
Results: ARF was found to occur in 0.4% (2/501) cases of mild preeclampsia, in 16.76% (28/167) cases of severe preeclampsia and in 9.72% (14/144) cases of eclampsia. Intrauterine death (14, 31.82%) was the commonest complication followed by HELLP syndrome (11, 25.0%), post-partum hemorrhage (8, 18.18%) and maternal death (7, 15.9%). Out of 44 cases, 14 (31.82%) had intrauterine death and 8 (18.18%) had fresh stillbirth. Sixteen (36.36%) had low birth weight babies. Total neonatal mortality in present study was observed in 5 (11.36%) cases, 3 in severe preeclampsia group and 2 in eclampsia group.
Conclusions: Acute renal failure is seen frequently in patients of severe preeclampsia and eclampsia with associated complications. Maternal and perinatal mortality and morbidity can be prevented in them with earlier detection and management of complications.
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References
Sibai B, Dekker G, Kupferminc M. Preeclampsia. Lancet 2005;365(9461):785-99.
Sibai B. Prevention of preeclampsia: a big disappointment. Am J Obstet Gynaecol 1998;179(5):1275-78.
Gabbe SG, Niebyl JR, Simpson JL, Landon MB, Galan HL, Jauniaux ERM, and Driscoll DA: Obstetrics: Normal and Problem Pregnancies, Saunders Elsevier, 6th Edition, 2012.
Sibai BM, Villar MA, Mabie BC. Acute renal failure in hypertensive disorders of pregnancy. Am J Obstet Gynecol 1990;162(3):777-83.
Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000;183:S1-S22.
Sanyal MK, Bhattacharjee A, Pattanyak A. A clinical review of eclampsia in a rural medical college of West Bengal (A three and half year study). J Obstet Gynecol India. 1987;37:797-802.
Verawalla NY, Ghamande S, Ingle KM. A five-year analysis of eclampsia. J Obstet Gynecol India 1989;513-15.
Thomas T, Jophy R, Mhaskar A, Misquith D. Are we increasing serious maternal morbidity by postponing termination of pregnancy in severe preeclampsia/eclampsia? J Obstet Gynecol India. 2005;25(4):347-51.
Prakash J, Pandey CK, Singh AK, Kar B. Hypertension in pregnancy: hospital-based study. J Assoc Physicians India. 2006;54(R):273-8.
Lopez-Liera M. Complicated eclampsia. Fifteen years’ experience in a referral medical centre. Am J Obstet Gynecol 1982;142(1):28-35.
Mattar F, Sibai BM. Eclampsia: Risk factor for maternal mortality. Am J Obstet Gynecol. 2000;182(2):306-12.
Mjahed K, Alaovi SY, Barrou L. Acute renal failure during eclampsia: Incidence, risk factors and outcome in intensive care unit. Renal failure 2004;26(3):215-21.
Drakeley A, Roure PA, Anthony J, Penny J. Acute renal failure complicating severe preeclampsia requiring admission to an obstetric intensive care unit. Am J Obstet Gynecol 2002;186(2):253-6.
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