Chorioamnionitis at the Befelatanana university hospital centre of obstetric gynecology in Antananarivo Madagascar: epidemiology, taken care and forecast

Authors

  • Rakotonirina Martial Department of Gynecology Obstetrics, Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar
  • Rainibarijaona L. N. A. Department of Gynecology Obstetrics, Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar
  • Rakotozanany Besaina Department of Gynecology Obstetrics, Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar
  • Randriamahavonjy Romuald Department of Gynecology Obstetrics, Soavinandriana Hopital Center, Antananarivo, Madagascar
  • Tsifiregna R. L. Department of Pediatrics, Tanambao University Hospital Centre in Diego, Madagascar
  • Housni Ibrahim Department of Gynecology Obstetrics, Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar
  • Hery Rakotovao A. Department of Gynecology Obstetrics, Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20202707

Keywords:

Choriamniotitis, Forecast, Maternofetal infection, Premature break of membranes

Abstract

Background: The chorioamnionitis corresponds to an infection of the ovular cavity. She puts game neonatal and maternal forecast. This study had as objectives to describe the epidemiological aspects, the taking care and the forecast of the chorioamnionitis to the gynecology teaching hospital and obstetrics Befelatanana, Madagascar.

Methods: It is about a descriptive, retrospective and transverse study, during a period of 6 months going from January, 2016 till July 2016. The pregnant women introducing a premature break of membranes (RPM) complicated with chorioamnionitis hospitalized in CHU-GOB during this period had been included.

Results: Authors found 35 cases of chorioamnionitis, that is 38.1% premature breaks of membranes. The medium age of the patients was 20±5, 16 years old (extreme from 17 to 36 years). Primiparous was found in 82.9%. The chorioamnionitis had happened in 68.5% cases after 37 weeks of amenorrhea. The delay between RPM and happened of chorioamnionitis was of 6 hours. The picture of chorioamnionitis was complete in 54.3%. Delivery was by low way in 33.3%. Authors had found 88.60% case of endometritis, 8.6% case of parietal suppuration post caesarian section but without any maternal decease. Neonatal complications were marked by a score of Apgar <7 - five minutes in 74.3%, neonatal infection in 25.7% and precocious neonatal decease in 11.4%.

Conclusions: The chorioamniotite concerned primiparous especially young urgent. The application of the protocol of taking care of the premature break of membranes is necessary for the reduction of the happening of the chorioamniotitis.

References

Redline RW. Inflammatory response in acute chorioamnionitis. Sem Fetal Neonat Med. 2012;17:20-5.

Redline RW. Placental inflammation. Sem Neonat 2004;9:265-74.

Gravett MG, Novy MJ, Rosenfeld RG, Reddy AP, Jacob T, Turner M, et al. Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers. JAMA. 2004;292:462-9.

Saizonou J, Ouédraogo L, Paraiso MN, Ayélo P, Kpozèhouen A, Daraté R, et al. Epidemiology and management of intrapartum infections in the maternity ward of Ouémé-Plateau county hospital in Benin. The Pan African Med J. 2014;17:89.

Beucher G, Charlier C, Cazanave C. Diagnosis and management of intra-uterine infection: CNGOF preterm premature rupture of membranes guidelines. Gynecol Obstet Fertil Senol. 2018;46(12):1054-67.

Yasmina A, Barakat A. Prelabour rupture of membranes (PROM) at term: prognostic factors and neonatal consequences. The Pan African Med J. 2017;26:68.

Laibl V, Sheffield J, Roberts S. Recurrence of clinical chorioamnionitis in subsequent pregnancies. Obstet Gynecol. 2006;108:1493-67.

Ronzino-Dubost V, Sananès N, Lavaux T, Youssef C, Gaudineau A, Lecointre L, et al. Evaluation of the interest of procalcitonin in the diagnosis of chorioamnionitis in preterm premature rupture of membranes. An observational and prospective study. J Gynecol Obstet Bio Reprod. 2016;45(7):745-53.

Horo A, Toure´-Ecra F, Mohamed F, Koné M. Malfunction and mortality kindergarten. Analysis of 35 cases at the maternity hospital of Yopougon University Hospital (Abidjan Côte d'Ivoire). Med Afr Noire. 2008;55(8):44-53.

Berardi JC, Colaou JC, Engelmann P, Botto JN, Vice P, Robichez B. Study of the bacterial colonization of the amniotic fluid collected by amniocentesis in the event of premature rupture of the membranes. J Gynecol Obstet Biol Reprod. 1995;24:69-73.

Gomez R, Romero R, Edwin SS, David C. Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection. Infect Dis Clin North Am. 1997;11(1):135-76.

Allen SR. Epidemiology of premature rupture of the fetal membranes. Clin Obst Gynecol. 191;34:685-93.

French JI, Mc Gregor JA. The pathobiology of premature rupture of membranes. Curr Opin Obstet Gynecol. 1995;7:140-5.

Paumier A. Rupture premature des membranes avant 32 semaines amenorrhea: factors prostitute prenatal. Gynecol Osterie Fertil. 2008;36:748-56.

Grether JK. Maternal infection and cerebral palsy in infants of normal birth weight. JAMA. 1997;278:207-11.

Lamy CS, Zuily E, Perdriolle E, Gauchotte S, Villeroy-de-Galhau MO, Delaporte D, et al. Management of post-partum infections. J Gyne Obstet Bio Reprod. 2012;41:886-903.

Jacques S, Laurent Ô, Moussiliou NP, Paul A, Alphonse K, René D, et al. Epidemiology and management of per-partum infections at the maternity ward of the Ouémé Plateau Hospital in Benin. Pan Afr Med J. 2014;17:82.

Downloads

Published

2020-06-25

Issue

Section

Original Research Articles