Outcomes of prolonged preterm premature rupture of the membrane: a report of six cases
Keywords:Foetal outcomes, Maternal outcomes, Premature rupture of membrane
Preterm premature rupture of the membranes (PROM) is associated with significant maternal morbidity and perinatal mortality. With an increasing era of infertility, the main interest of an assisted reproductive technology specialist is to increase the take-home baby rate. Here authors present report on the outcomes of prolonged preterm PROM cases facilitated with expectant management. Report is based on the medical records of six women with preterm PROM between 16-31 weeks of gestation who gave their consent to continue the pregnancy. These women were diagnosed with PROM by the litmus test and per speculum examination. Ultrasound scan and clinical investigation, which included complete blood count and C-reactive protein level, were performed in all cases. Prophylactic antibiotics were administered to prevent the infection and increase the latency period. All six babies (100%) were delivered successfully. There was no foetal mortality and maternal morbidity observed. Expectant management in preterm PROM cases can increase the survival rate and hence the take-home baby rate.
Tielsch JM. Global Incidence of Preterm Birth. Nestle Nutrition Institute workshop series. 2015;81:9-15.
Kim M, Lee HJ, Choi SJ, Oh SY, Roh CR, Kim JH. An extremely rare case of hand prolapse with preterm premature rupture in the membrane of one twin. Obstet Gynecol Sci. 2018;61:413-6.
Endale T, Fentahun N, Gemada D, Hussen MA. Maternal and fetal outcomes in term premature rupture of membrane. World J Emerg Med. 2016;7:147.
Modena AB, Kaihura C, Fieni S. Prelabour rupture of the membranes: recent evidence. Acta Biomed. 2004;75:5-10.
American College of Obstetricians and Gynecologists. Practice Bulletin No. 172: Premature Rupture of Membranes. Obstet Gynecol. 2016;128(4):e165.
Galinsky R, Polglase GR, Hooper SB, Black MJ, Moss TJ. The consequences of chorioamnionitis: preterm birth and effects on development. J Preg. 2013;2013.
Halima T. Premature rupture of membranes at week 19: favorable pregnancy outcome and four years follow-up after expectant management. Int J Gynaecol Obstet. 2010;14(2).
Haas DM, Benjamin T, Sawyer R, Quinney SK. Short-term tocolytics for preterm delivery – current perspectives. Int J Womens Health. 2014;6:343-9.
Hsu TL, Hsu TY, Tsai CC, Ou CY. The experience of amnioinfusion for oligohydramnios during the early second trimester. Taiwan J Obstet Gynecol. 2007;46(4):395-8.
Hofmeyr GJ, Essilfie-Appiah G, Lawrie TA. Amnioinfusion for preterm premature rupture of membranes. Cochrane Database Syst Rev. 2011;12.
Yang LC, Taylor DR, Kaufman HH, Hume R, Calhoun B. Maternal and fetal outcomes of spontaneous preterm premature rupture of membranes. J Am Osteopat Assoc. 2004;104:537-42.