Coexistence of both Brenner tumor and cystadenofibroma of ovary in a postmenopausal woman: a rare case

Authors

  • B. Kalpana Department of Reproductive Medicine, Guru Hospital, Madurai, Tamil Nadu, India
  • Soumya Ranjan Panda Department of Reproductive Medicine, Guru Hospital, Madurai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20190907

Keywords:

Brenner tumor, Cystadenofibroma, Frozen section, Salpinoophorectomy

Abstract

Brenner tumor, and cystadeno fibroma of ovary are rare varieties of ovarian tumor, characterized by presence of solid components. There are very rare instances where both Brenner tumor and cystadenofibroma coexist in a single patient. A 48-year P1L1, postmenopusal woman presented at Guru hospital, Madurai, with chief complaints of on and off postmenopausal bleeding for 6 months. On ultrasonography there were two simple cysts of ovary measuring 6x 6 cm on left side and 4x4 cm on right side. She was managed with total laparoscopic hysterectomy and bilateral salpingoophorectomy.  Intraoperatively there was a right ovarian mass of 6x6 cm size and a left ovarian mass of 4x4 cm size. Left ovarian mass reported as benign cystadenofibroma while the right ovarian mass was reported to be brenners tumor on histopathology. As the preoperative imaging are not completely relied for diagnosing these tumors, awareness of the surgeons of these entities is particularly important. The prognosis of both of these tumors is excellent with suitable treatment. They have a very low recurrence risk on compete removal through surgery.

References

De Cecio R, Cantile M, Collina F, Marra L, Santonastaso C, Scaffa C, Botti G, Losito NS. Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study. J Ovarian Res. 2014;7(1):101.

Devouassoux-Shisheboran M, Genestie C, Ray-Coquard I. [Dualistic classification of epithelial ovarian cancer: is it clinically relevant?] Bull Cancer. 2016;103(3):252-8.

Hemalatha AL, Konanahalli P. Bilateral malignant Brenner tumor of ovary. J Obstet Gynecol India. 2005;55(1):81-2.

Cho SM, Byun JY, Rha SE, Jung SE, Park GS, Kim BK, et al. CT and MRI findings of cystadenofibromas of the ovary. Eur Radiol 2004;14(5):798-804.

Kuhn E, Ayhan A, Shih IM, Seidman JD, Kurman RJ. Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium. Eur J Cancer. 2013; 49(18):3839-49.

Ingin RJ, Andola SK, Zubair AA. Transitional cell carcinoma of the ovary: case series and review of literature. J Clin Diagn Res. 2014;8(8):FD07-8.

Borah T, Bora BD, Mahanta RK and Saikia S. Brenner tumor of ovary: An incidental finding. J Midlife Health. 2011;2(1): 40.

Jung DC, Kim SH, Kim SH. MR imaging findings of ovarian cystadenofibroma and cystadenocarcinofibroma: clues for the differential diagnosis. Korean J Radiol. 2006;7(3):199-204.

Alcázar JL, Errasti T, Mínguez JA, Galán MJ, García-Manero M, Ceamanos C. Sonographic features of ovarian cystadenofibromas: spectrum of findings. J Ultrasound Med.2001; 20(8):915-9.

Takeuchi M, Matsuzaki K, Kusaka M, Shimazu H, Yoshida S, Nishitani H, et al. Ovarian cystadenofibromas: Characteristic magnetic resonance findings with pathologic correlation. J Comput Assist Tomogr. 2003;27(6):871-3.

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Published

2019-02-26

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Section

Case Reports