Study of maternal and fetal outcome in HIV positive women on HAART therapy in a tertiary hospital

Priya Shankar; Madhu J.

doi:10.18203/2320-1770.ijrcog20190311

Authors

Priya Shankar Department of Obstetrics and Gynecology, Karnataka Institute of Medical Sciences, Hubli, Bangalore, Karnataka, India
Madhu J. Department of Obstetrics and Gynecology, Karnataka Institute of Medical Sciences, Hubli, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20190311

Keywords:

Fetal outcome, HAART, Maternal outcome

Abstract

Background: India has the third largest population of HIV. Moving from single dose nevirapine in labor to use of HAART treatment for all pregnant women and the outcome of the same was the subject of present study.

Methods: Retrospective study of HIV positive pregnant women on HAART treatment admitted in labor room at Karnataka institute of medical sciences from June 2015 to December 2016. A retrospective analytical study of 93 women with HIV positive status on HAART therapy admitted in labor at KIMS was done by collecting data from case records. Baby follow up details were collected from ART center, KIMS.

Results: Parameters studied were maternal and fetal outcomes. Maternal outcome in terms of mode of delivery, morbidity and mortality and fetal outcomes in terms of APGAR at birth, weight of the baby, NICU admission, incidence of meconium, still birth and intrauterine fetal demise, follow up of the babies at 6 weeks, 6 Months and 18 Months for seropositivity.

Conclusions: HAART in pregnant women significantly improved the maternal and fetal outcomes.

Metrics

Metrics Loading ...

References

HIV facts and figures/NationalAIDS control organization/MoHFW/GOI. Available at: naco.gov.in>hiv-facts-figures.

National AIDS control organization, annual report 2014-15. Available at: www.naco.gov.in/naco/quick link/publication/annual report/annual-report-NACO-2014-15.

NACO annual report 2012-13. Available at: www.naco.gov.in/annual report 2012-13.

WHO- Mother to child transmission of HIV- World Health Organization. Available at: https://www.who.int>hiv>topics>mtct.

Palumbo P, Linsey JC, Hughes MD, Cotton MF, BobatR, Meyesr T, et al. Antiretroviral treatment for children with peripartum nevirapine exposure. N Engl J Med. 2010;363:1510-20.

Crowley S, Rollins N, Shaffer N, Guerma T, Vitoria M, Lo YR. New WHO HIV treatment and prevention guidelines. Lancet. 2010;375:874-5.

National AIDS Control Organisation. National AIDS Control Policy-annual report 2015-16. 2016;335-97.

National guidelines for prevention of parent to child transmission Naco. gov.in. prevention of parent to child transmission (PPTCT).

Alemu FM, Yalew AW, Fantahun M, Ashu EE. Antiretroviral therapy and pregnancy outcomes in developing countries: a systematic review. Int J MCH AIDS. 2015;3(1):31.

Olagbuji BN, Ezeanochie MC, Ande AB, Oboro VO. Obstetric and perinatal outcome in HIV positive women receiving HAART in urban Nigeria. Archives Gynecol Obstet. 2010;281(6):991-4.

Haeri S, Shauer M, Dale M, Leslie J, Baker AM, Saddlemire S, et al. Obstetric and newborn infant outcomes in human immunodeficiency virus-infected women who receive highly active antiretroviral therapy. Am J Obstet Gynecol. 2009;201(3):315-e1.

Dadhwal V, Sharma A, Khoiwal K, Deka D, Sarkar P, Vanamail P. Pregnancy outcomes in HIV-infected women: experience from a tertiary care center in India. Int J MCH AIDS. 2017;6(1):75.