Clinicopathologic study of large abdominal masses in gynaecological practice and their outcome
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20160399Keywords:
Abdominal mass, Gynecological mass, Ovarian tumourAbstract
Background: In female reproductive tract the differential diagnosis of pelvic mass is quite variable because abnormality may arise from gynaecological or non-gynaecological origin. The aim of the present study is to find out the causes why these patients come with large abdominal masses, to find out the risk factors and to do proper management.
Methods: This study is a retrospective study of all cases of large abdominal mass All the patient coming with palpable abdominal and pelvic adnexal mass in the gynaecologic OPD were included in the study. Study population included women of all ages and the relevant population of women with treatment for fibroids and ovarian mass. The data was analysed retrospectively and the results were computed accordingly.
Results: Incidence of large ovarian mass was found out to be 2.82% and of large fibroid was 2.31%. Our study showed the peak incidence of ovarian tumors in age group more than 40 years. 90.5% of patients were illiterate and only 10 patients were literate. In the study only 8.57% patients had addiction to some drug and all were tobacco chewer. The incidence of benign tumor was 83.33% (commonest being ovarian tumours) and that of malignant tumors is 16.66%.
Conclusions: Ultrasound is effective in detecting the abdominal mass, size and type of abdominal mass, so that early diagnosis can be done and treatment can be given as soon as possible. Apart from already established risk factors, obesity and uterine fibroid have an important association.
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References
Parazzini F, Negri E, La Vecchia C. Reproductive factors and risk of uterine fibroids. Epidemiol. 1996;7:440-2.
Marshall LM, Spiegelman D, Goldman MB. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertil Steril. 1998;70:432-9.
Lumbiganon P, Rugpao S, Phandhu-fung S. Protective effect of depot-medroxyprogesterone acetate on surgically treated uterine leiomyomas: a multicenter case-control study. Br J Obstet Gynecol. 1996;103:909-14.
Musey VC, Collins DC, Musey PI. Age-related changes in the female hormonal environment during reproductive life. Am J Obstet Gynecol. 1987;157:312-7.
Dorgan JF, Reichman ME, Judd JT. Relationships of age and reproductive characteristics with plasma estrogen and androgens in premenopausal women. Cancer Epidemiol Biomarkers Prev. 1995;4:381-6.
Bernstein L, Pike MC, Ross RK. Estrogen and sex hormone- binding globulin levels in nulliparous and parous women. J Natl Cancer Inst. 1985;74:741-5.
Musey VC, Collins DC, Brogan DR. Long term effects of a first pregnancy on the hormonal environment: estrogens and androgens. J Clin Endocrinol Metab. 1987;64:111-8.
Musey VC, Collins DC, Musey PI. Long-term effect of a first pregnancy on the secretion of prolactin. N Engl J Med. 1987;316:229-34.
Windham GC, Elkin E, Fenster L. Ovarian hormones in premenopausal women: variation by demographic, reproductive and menstrual cycle characteristics. Epidemiol. 2002;13:675-84.
Mora S, Diehl T, Stewart EA. Prolactin is an autocrine growth regulator for human myometrial and leiomyoma cells. J Soc Gynecol Invest. 1995;2:396.
Kawaguchi K, Fujii S, Konishi I. Immuno histochemical analysis of oestrogen receptors, progesterone receptors and Ki-67 in leiomyoma and myometrium during the menstrual cycle and pregnancy. Virchows Arch A Pathol Anat Histopathol. 1991;419:309-15.
Walker CL, Cesen-Cummings K, Houle C. Protective effect of pregnancy for development of uterine leiomyoma. Carcinogenesis. 2001;22:2049-52.
Faerstein E, Szklo M, Rosenshein N. Risk factors for uterine leiomyoma: a practice-based case-control study. I. African-American heritage, reproductive history, body size, and smoking. Am J Epidemiol. 2001;153:1-10.
Lambe M, Wuu J, Weiderpass E. Childbearing at older age and endometrial cancer risk (Sweden). Cancer Causes Control. 1999;10:43-9.
Glass AR. Endocrine aspects of obesity. Med Clin North Am. 1989;73:139-60.
Schneider J, Bradlow HL, Strain G, Levin J, Anderson K, Fishman J. Effects of obesity on estradiol metabolism: decreased formation of nonuterotropic metabolites. J Clin Endocrinol Metab. 1983;56:973-8.
Spinos N, Terzis G, Crysanthopoulou A, Adonakis G, Markou KB, Vervita V, Koukouras D, Tsapanos V, Decavalas G, Kourounis G, Georgopoulos NA. Increased frequency of thyroid nodules and breast fibroadenomas in women with uterine fibroids. Thyroid. 2007;17:1257-9.
Olive DL, Lindheim SR, Pritts EA. Non-surgical management of leiomyoma: impact on fertility. Curr Opin Obstet Gynecol. 2004;16(3):239-43.
Buttram VC Jr, Reiter RC. Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril. 1981;36(4):433-45.
Frank TS, Manley SA, Olopade OI, Cummings S, Garber JE, Bernhardt B et al. Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. J Clin Oncol. 1998;16:2417-25.
Fox H, Langley FA. The development of the gonads. Fox H, Langley FA (Eds.). In: Tumors of the Ovary. London: William Heinemann Medical Books Limited; 1976:19-28.
Neerja Bhatla. Tumors of the ovary. In: Neerja Bhatla (Ed.) In: Jeffcoate’s Principles of Gynaecology. 5th Ed. London: Arnold; 2001:524-525.
Smith LH, Morris CR, Yasmeen S, Parikh-Patel A Cress RD, Romano PS. Ovarian cancer: can we make the clinical diagnosis earlier? American Cancer Society. 2005. DOI: 10.1002/cncr.21310.
Shattuck EP, Mcclure M, Somard J, Labrie F, Narod S, Cough F et al. Collaborative survey of 80 mutations in the BRCA I breast and ovarian cancer susceptibility gene: Implications for presymptomatic testing and screening. JAMA. 1995;273:535-41.
Berek JS. Ovarian Cancer. In: Berek JS (Ed.): Novak’s Gynecology, 13th Ed. Lippincott Williams and Wilkins; 2002:1262.
Roth LM, Dallenbach-Hellweg G, Czernobilsky B. Ovarian Brenner Tumors. I. Metaplastic proliferating and of low grade potential. Cancer. 1985;56:582-91.
Berek JS, Hacker NF. Staging and second-look operations in ovarian cancer. In: Alberts DS, Surwit EA, eds. Ovarian Cancer: Boston: Martinus Nijhoff, 1985;109-127.
Jha R, Karki S. Histological pattern of ovarian tumors and their distribution. Nepal Med Coll J. 2008;1081-5.
Ahmed Z, Kayani, HAsan SH, Muzaffar S, Gill MS. Histological pattern of ovarian neoplasm. Pak Med Association. 2000;501:416-9.
Zeake JF, currie JL, Rosenshein NB, Woodruff JD Long term follow-up of serous ovarian tumors of low malignant potential. Gyne Col Oncol. 1992; 47:1508.
Bhattacharya MM, Shindey SD, Purandare, VN. A clinic-pathological analysis of 270 ovarian tumors. J Postgrade Med. 1980;26:103.
Kayastha S. Study of ovarian tumor in Nepal Medical College teaching hospital. Nepal Med Coll J. 2009;11:2002.
Prabhakar BR, Maingi K. Ovarian tumors. Prevalence in Punjab. Indian J Pathol Microbiol. 1989;32:276-81.
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