Self limiting fetal bradycardia associated with maternal evidence of dengue and chikungunya virus co-infection: a case report

Authors

  • Alka Goel Department of Obstetrics and Gynecology, PGIMER and Dr. RML Hospital, New Delhi, India
  • Anupriya Narain Department of Obstetrics and Gynecology, MAMC and Lok Nayak Hospital, New Delhi, India
  • Atul Goel Department of Medicine, PGIMER and Dr. RML Hospital, New Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20191976

Keywords:

Bradycardia, Chikungunya, Dengue, Fetal, Intrapartum, Self-limiting

Abstract

Dengue and chikungunya infections are commonly encountered by the clinicians in a tropical country like India. We report this case to emphasize the rare manifestations of self-limiting intrapartum bradycardia in fetuses of chikungunya and dengue infected mothers. A primigravida at 32 weeks of gestation presented with history of fever for one day. The blood investigations were positive for both dengue and chikungunya virus infection. On the third day of fever, NST showed a low baseline fetal heart rate of 95 to 100 beats per minute but good beat to beat variability and three accelerations in 10 minutes. This pattern persisted for 48 hours. Although, the finding initially appeared alarming, the change in baseline heart rate of fetus was transient and self-limiting and recovered completely. Hence, a judicious approach and close fetal surveillance can avoid hasty decisions regarding an early termination of pregnancy.

Metrics

Metrics Loading ...

References

Villamil- Go`mez WE, et al. Zika, dengue, and chikungunya co infection in a pregnant woman from Columbia Int j Infect Dis. 2016 Oct;51:135-138.

Salgado DM, Eltit JM, Manfield K, César Panqueba DVM, Castro D, et al. Heart and skeletal muscle are targets of dengue virus infection. Pediatr Infect Dis J. 2010;29(3):238-42.

Bodenmann P, Genton B. Chikungunya: an epidemic in real time. Lancet. 2006;368(9531):258.

Ge ́ rardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, et al. Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Re ́union. PLoS Med. 2008;5:e60.

Alvarez MF, Bolívar-Mejía A, Rodriguez-Morales AJ, Ramirez-Vallejo E. Cardiovas-cular involvement and manifestations of systemic chikungunya virus infection: A systematic review. F1000Res. 2017;6:390.

Torres JR, Falleriou-Arlant LH, Duenas L, Pleitez-Navarrete J, Salgado DM, Castillo JBD. Congenital and perinatal complications of chikungunya fever: a Latin American experience. Int J Infect Dis. 2016;51:85-8.

Escobar M, Neito AJ, Loaiza-Osorio S, Barona JS, Rosso F. Pregnant women hospitalized with chikungunya virus infection, Columbia 2015. Emer Infect Dis. 2017;23(11):1777-83.

Roze ́ B, Najioullah F, Signate A, Apetse K, Brouste Y, Gourgoudou S, et al. Zika virus detection in cerebrospinal fluid from two patients with encephalopathy, Martinique, February 2016. Euro Surveill. 2016;21.

Kumar D, Sanjeev RK. A rare manifestation pf congenital dengue infection. HK J Paediatr (new series). 2016;21:204-6.

Ribeiro CF, Lopes VGS, Brasil P, Pires ARC, Rohloff R, Nogueira RMR. Dengue infection in pregnancy and its impact on the placenta. Int J Infect Dis. 2017;55:109-12.

Couderc T, Chretien F, Schilte C, Disson O, Brigitte M, Guivel-Ben-hassine F et al. A mouse model for chikungunya: young age and inefficient type-I interferon signalling are risk factors for severe disease. PLoS Pathog. 2008;4:e29.

Promphan W, Sopontammarak S, Pruekpraset P, Kajornwattankul W, Kongpattanayothin A. Dengue myocarditis. Southeast Asian J Trop Med Public Health. 2004;35(3):611-3.

Downloads

Published

2019-04-29

How to Cite

Goel, A., Narain, A., & Goel, A. (2019). Self limiting fetal bradycardia associated with maternal evidence of dengue and chikungunya virus co-infection: a case report. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 8(5), 2103–2105. https://doi.org/10.18203/2320-1770.ijrcog20191976

Issue

Section

Case Reports