A comparative study of low dose vaginal misoprostol and dinoprostone gel for induction of labour at term of pregnancy

Authors

  • . Kalpana Department of Obstetrics and Gynaecology, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India
  • Priya Sharma Department of Obstetrics and Gynaecology, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India
  • Amit Kaushik Department of Community Medicine, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India
  • Priyanka Rao Department of Community Medicine, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India
  • Neelam Swaroop Department of Community Medicine, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India
  • Neetu Singh Department of Community Medicine, Uttar Pradesh University of Medical, Saifai, Etawah, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20164659

Keywords:

Dinoprostone gel, Labour induction, Labour analgesia, Misoprostol

Abstract

Background: The aim of this study was to compare the low dose of vaginal misoprostol and dinoprostone gel for the induction of labour at term of pregnancy.

Methods: The study was conducted on 90 women, randomized into two groups, each group having 45 women. First group received misoprostol per vaginally and second group received the dinoprostone gel. The duration of induction to delivery interval, mode of delivery and complications related to labour or foetus were recorded.

Results: The mean induction to delivery interval in the misoprostol group was 11.68 ± 4.49 hours and in the dioprostone gel group was 14.85 ± 7.08 hours. Applying the modified t-test, this difference is statistically significant (P value 0.004). Thus misoprostol leads to early labour and early delivery as compared to dinoprostone gel.

Conclusions: As shown in this study, vaginal misoprostol is highly effective induction agent with no adverse effect on the outcome of labour as compared to dinoprostone gel.

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References

Shivarudraiah G, Palaksha MA. A randomized controlled trial comparing low dose vaginal misoprostol and dinoprostone gel for labor induction. J Obstet Gynaecol India. 2011;2:153-60.

Greagson S, Waterstone M., Norman I., Murrells T. A randomized controlled trial comparing low dose vaginal misoprostol and dinoprostone vaginal gel for inducing labour at term. BJOG. 2005;112:438-44.

Sheela CN, Mhaskar A, George S. Comparison of vaginal misoprostol and oral misoprostol with intracervical dinoprostol gel for induction of labour at term. J Obstet Gynecol India. 2007 July/Aug;57(4):327-30.

Latika S, Biswajit C. Comparison of prostaglandin E1 (Misoprostol) with prostaglandin E2 (Cerviprime) for labour induction. J Obstet Gynecol India. 2004;54(2):139-42.

Murthy BK, Arkalgud MS. Misoprostol alone versus a combination of cerviprime and oxytocin for induction of labour. J Obstet Gynecol India. 2006;56(5):413-6.

Ozkan S, Caliskan E. Comparative safety and efficacy of vaginal Misoprostol versus cerviprime vaginal insert in labour induction at term: a randomized trial. Arch Gynecol Obstet. 2009;280(1):19-24.

Cheng SY, Ming H, Lee JC. Titrated oral compared with vaginal misoprostol for labor induction: a randomized controlled trial. Obstet Gynecol. 2008;111:119-25.

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Published

2016-12-20

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Section

Original Research Articles