Published: 2019-07-26

Gestational diabetes mellitus, Vitamin D status and fetomaternal outcome

Rekha T., Shazia Parveen, Nasreen Noor, Seema Hakim, Shagufta Moin


Background: Diabetes is the most common medical complication of pregnancy. Vitamin D deficiency which was initially considered only to influence bone metabolism, is now known to exert a wide spectrum of extra-skeletal effects. Vitamin D deficiency is closely associated with gestational diabetes mellitus, it also leads to adverse maternal and child outcome. Objective of this study was to compare the vitamin D levels in healthy pregnant women and women with gestational diabetes mellitus and to observe the feto-maternal outcome.

Methods: This prospective study was carried out on 160 pregnant women between the age group 20-40 years attending the Obstetrics and Gynaecology department of JNMC, AMU, Aligarh from October 2016 to October 2018. Women were divided into group A- normal pregnant women and group B- women with GDM. Estimation of vitamin D was done in both the groups.

Results: Mean vitamin D levels were lower in women with GDM as compared to normal pregnant women.

Conclusions: Women with vitamin D deficiency have an increased risk of developing GDM and adverse feto maternal outcome as compared to those who had normal level of vitamin.


Fetal outcome, Gestational diabetes mellitus, Maternal outcome, Vitamin D

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