Embryonal rhabdomyosarcoma of the uterine cervix: a rare case report

Authors

  • Ariana R. Gomes Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Pedro B. Leite Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Juliana S. Rocha Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Pedro V. Enes Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Joana I. Carvalho Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Ana R. Pinto Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
  • Fernanda M. Costa Department of Obstetrics and Gynaecology, Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20164683

Keywords:

Adolescent neoplasm, Embryonal rhabdomyosarcoma, Sarcoma botryoides, Uterine cervix neoplasm

Abstract

Embryonal rhabdomyosarcoma of the female genital tract is a rare tumour. It tends to occur during childhood in the vagina and, rarely, it can arise in the uterine cervix, with a peak incidence in the second decade. We report a case of a 18-year-old female with an embryonal rhabdomyosarcoma (sarcoma botryoides) presenting himself as a cervical polyp. This tumour consisted of rhabdomyoblasts with miscellaneous differentiation surrounded by a loose, myxoid stroma. The patient was successfully treated with cervical conization and adjuvant chemotherapy. She is now disease-free at the 28th month follow-up. Awareness of this uncommon lesion in the cervix and its clinical implications is important to prevent misdiagnosis. Therapy has recently inclined to conservative and fertility-sparing treatment.

References

Behtash N, Mousavi A, Tehranian A, Khanafshar N, Hanjani P. Embryonal rhabdomyosarcoma of the uterine cervix: case report and review of the literature. Gynecol Oncol. 2003;91:452-5.

Daya DA, Scully RE. Sarcoma botryoides of the uterine cervix in young women: a clinicopathological study of 13 cases. Gynecol Oncol. 1988;29:290-304.

Ghaemmaghami F, Zarchi MK, Ghasemi M. Lower genital tract rhabdomyosarcoma: case series and literature review. Arch Gynecol Obstet. 2008;278:65-9.

Scaravilli G, Simeone S, Orabona GDA, Capuano S, Serao M, Rossi R et al. Case report of a sarcoma botryoides of the uterine cervix in fertile age and literature review. Arch Gynecol Obstet. 2009;280:863-6.

Dehner L.P., Jarzembowski J.A., Hill D.A. Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations. Mod. Pathol. 2012;25(4):602-14.

Bernal KL, Fahmy L, Remmenga S, Julia B, Baker J. Embryonal rhabdomyosarcoma (sarcoma botryoides) of the cervix presenting as a cervical polyp treated with fertility-sparing surgery and adjuvant chemotherapy. Gynecol Oncol. 2004;95:243-6.

Melo A, Amorim-Costa C, Pires MC, Fernandes D, Soares M, Cambão M, et al. Botryoid rhabdomyosarcoma of the uterine cervix: a case report. Journal Obstet and Gynaecol. 2012;7:709-711.

Ayas S, Uygur L, Bostanci E, Gürbüz A. A successful pregnancy during the treatment of cervical sarcoma botryoides and advantage of fertility sparing management: A case report: Iran J Reprod Med. 2015;13(2):113-6.

Bouchard-Fortier G, Kim RH, Allen L, Gupta A, May T. Fertility-sparing surgery for the management of young women with embryonal rhabdomyosarcoma of the cervix: A case series. Gynecol Oncol Rep. 201626;18:4-7.

Downloads

Published

2016-12-20

Issue

Section

Case Reports