Prospective comparative study between colposcopy and histopathology for diagnosis of CIN and carcinoma cervix

Kishorkumar Hol, Shweta S. Mishra, Sameer Darawade, Hemant Damle


Background: Cervical cancer develops from precursor lesions and detection of these lesions is of utmost importance. The detection of precancerous lesions is made with help of screening tests most important include PAP smear and colposcopy. So we conducted this study to understand the role of colposcopy in down staging of Carcinoma cervix.

Methods: We performed a prospective study between Jan 2018 to Dec 2018 on 180 subjects chosen from patients who sought consultation for various gynaecological complaints between age group of 18-60 years. A Pap smear followed by a colposcopy was performed and colposcopic directed biopsies were taken and subjected to histolopathological examination.

Results: Colposcopy had a sensitivity of 83.3%, specificity of 78.5%, PPV of 68.9% for CIN 1. It had a sensitivity of 90.9%, specificity of 95.2%, PPV of 83.33% for CIN 2 and 3 when co related with gold standard histopathology which is much higher as compared to Pap smear.

Conclusions: Colposcopy is an effective tool in down staging of Carcinoma cervix.


Carcinoma cervix, Cervical biopsy, CIN, Colposcopy, Pap smear

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