Gliomatosis peritonei arising in setting of immature teratoma of ovary: a case report

Authors

  • Dhruba Prasad Paul Department of Obstetrics and Gynecology, Agartala Government Medical College and GBP Hospital, Agartala, Tripura, India
  • Kashish Garg Department of Obstetrics and Gynecology, Agartala Government Medical College and GBP Hospital, Agartala, Tripura, India
  • Ashis Kumar Rakshit Department of Obstetrics and Gynecology, Agartala Government Medical College and GBP Hospital, Agartala, Tripura, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20194390

Keywords:

Abdominal mass, Chemotherapy, Gliomatosis, HPE, Immature teratoma, Laparotomy

Abstract

A 14 years old girl presented to the gynecology OPD with pain abdomen and huge abdominal lump since 2 months. On clinical examination, a large mass of 20x15 cm size was found extended upto the xiphoid process. Serum studies showed rise of CA-125 up to 406.9U/mL and LDH up to 310U/L. USG shows right ovarian cyst of 14.8x14.1x12.8 cm with internal calcification. MRI revealed a well encapsulated mass of 21x19x17cm with solid and cystic mass and upward peritoneal extension. Exploratory laparotomy was performed with right sided salpingo- ophorectomy with infracolic omentectomy, as the omentum appeared granular. She had an uneventful post-operative recovery. Subsequently HPE showed immature teratoma NORRIS grade 3 with co-existent peritoneal gliomatosis (grade 0). She is under regular follow-up and decided to give six cycles of combination chemotherapy with BEP at regional cancer hospital.

Metrics

Metrics Loading ...

References

Huang HC, Chen CH, Chu CC. Mature cystic teratoma of ovary with gliomatosis peritonei. J Med Sci. 2004;24:343-6.

Menéndez-Sánchez P, Villarejo-Campos P, Padilla-Valverde D. Gliomatosis peritonei: recurrence, treatment and surveillance. Cir Cir. 2011;79:256-9.

Galateanu AG, Terzea DC, Carsote M. Immature ovarian teratoma with unusual gliomatosis. J Ovarian Res. 2013;6:28.

Kraggerud SM, Szymanska J, Abeler VM, Kaern J, Eknaes M, Heim S, et al. DNA copy number changes in malignant ovarian germ cell tumors. Cancer Res. 2000;60:3025-30.

Heifetz SA, Cushing B, Giller R, Shuster JJ, Stolar CJ, Vinocur CD, Hawkins EP. Immature teratomas in children: pathologic considerations: a report from the combined Pediatric Oncology Group/ Children’s Cancer Group. Am J Surg Pathol. 1998;22:1115-24.

Das CJ, Sharma R, Thulkar S. Mature ovarian teratoma with gliomatosis peritonei-A case report. Indian J Cancer. 2005;42:165-7.

Abiko K, Mandai M, Hamanishi J, Matsumura N, Baba T, Horiuchi A, et al. Oct4 expression in immature teratoma of the ovary: relevance to histologic grade and degree of differentiation. Am J Surg Pathol. 2010;34:1842-8.

Pecorelli S, Benedet JL, Creasman WT, Stepherd JH. FIGO staging ofgynecologic cancer. 1994-1997 FIGO Committee on Gynecologic Oncology. International Federation of Gynecology and Obstetrics. Int J Gynaecol Obstet. 1999;65:243-9.

Norris HJ, Zirkin HJ, Benson WL. Immature (malignant) teratoma of theovary. A clinical and pathologic study of 58 cases. Cancer. 1976;37:2359-72.

Downloads

Published

2019-09-26

How to Cite

Paul, D. P., Garg, K., & Rakshit, A. K. (2019). Gliomatosis peritonei arising in setting of immature teratoma of ovary: a case report. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 8(10), 4097–4100. https://doi.org/10.18203/2320-1770.ijrcog20194390

Issue

Section

Case Reports