Study of fetomaternal outcome in cases of premature rupture of membrane at tertiary care rural institute of Western Uttar Pradesh, India

Jigyasa Singh, Vaibhav Kanti, Vandana Verma


Background: Premature rupture of membranes (PROM) is the rupture of the fetal membranes before the onset of labor. Preterm PROM complicates approximately 3 percent of pregnancies and leads to one third of preterm births. It increases the risk of prematurity and leads to a number of other perinatal and neonatal complications.

Methods: This was a prospective study carried out at the department of obstetrics and gynaecology, UPUMS, Saifai from April 2018 to September 2018 (6 months study). Patients with Spontaneous rupture of membranes any time beyond 28th week of pregnancy, but before the onset of labour. Patients with following conditions were excluded from the study- meconium stain liquor, cord prolapse, antepartum haemorrhage, active infection at other sites, active liver disease.

Results: A total of 103 cases of premature rupture of membrane (PROM) were recorded from April 2018 to September 2019 among 1523 admitted pregnant patients. Most of the patients 56 (54.36%) were delivered by caesarean section (C/S). Previous C/S, oligohydramnios, fetal distress, chorioamnionitis were the common indications for doing C/S. Forty-seven (45.63%) patients were delivered vaginally.

Conclusions: Most of the affected women belongs to 20-24 years of age (53.39%). Term PROM was more in comparison to PPROM and most of them were multigravidae. Cesarean section rate was high. Most common complication was of subclinical urogenital infection (51.02%).


Chorioamnionitis, Fetal distress, Neonatal complications, Oligohydramnios, Prematurity, Preterm PROM

Full Text:



Krishna UR, Shah MH. Prelabour Rupture of Membranes, Obstetrics and Gynecology for Postgraduates, edited by S.S. Ratnam, K. Bhasker Rao and S. Arulkumaran, 2nd edition; 1999;1:96-108.

Arias F, Daftary SN, Bhide AG. Premature Rupture of Membrane, Practical Guide to High-Risk Pregnancy and Delivery, A South Asian Perspective, 3rd edition; 2008:240-261.

Dutta DC. Prelabour Rupture of the Membranes, Text Book of Obstetrics, 6th edition; 2006:317-320.

Tasnim S. Clinical profile and outcome of pregnancy in premature rupture of membrane: a study in Dhaka Medical College Hospital. Dissertation; Bangladesh College of Physicians and Surgeons; 1995.

Begum A. Maternal and fetal outcome of premature rupture of membrane: one-year study in Dhaka Medical College Hospital. Dissertation; Bangladesh College of Physicians and Surgeons; 2001.

Begum N. Epidemiology of Premature Rupture of Membrane and Management in Rangpur Medical College Hospital. Dissertation; Bangladesh College of Physicians and Surgeons; 2004.

Bhalerao S, Desai A. Premature rupture of membranes. Jn: Saraiya UB, Rao KB, Chatterjee A, eds. Principles and Practice of Obstetrics and Gynecology (2nd edn). An FOGSI Publication. New Delhi: Jaypee Brothers; 2003:125.

Daftary SN, Desai SV. Preterm labour and premature rupture of membranes. In: Daftary SN, Desai SV, eds. Selected Topics in Obstetrics and Gynaecology (2nd edn). New Delhi: BI Publications; 2006:128.

Arias F, Tomich PH. Etiology and outcome of low birth weight and preterm infants. Obstet Gynecol. 1982;60:277-81.

Romero R, Yoon BH, Mazor M, Gomez R, Gonzalez R, Diamond MP, et al. A comparative study of the diagnostic performance of amniotic fluid glucose, white cell count, interleukin-6 and Gram stain in the detection of microbial invasion in patients with preterm premature rupture of the membranes. Am J Obstet Gynecol. 1993;169:839-51.

Johnson JWC, Daikoku NH, Niebyl JR, Johnson JT, Khouzami VA, Witter FR Premature rupture of membranes and prolonged latency. Obstet Gynecol. 1981;57:547-56.

Hein M, Helmig RB, Schønheyder HC, Ganz T, Uldbjerg N. An in vitro study of antibacterial properties of the cervical mucous plug in pregnancy. Am J Obstet Gynecol. 2001:185.

Pressman EK, Cavanaugh JL, Woods JR. Physical properties of the chrioamnion throughout gestation. Am J Obstet Gynecol. 2002;187;672-5.