DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20194903

Endometrial osseous metaplasia in a case of abnormal uterine bleeding

Himleena Gautam, Alaka Goswami, Papari Goswami, Kamal Kumar Kathar

Abstract


Endometrial osseous metaplasia is an uncommon pathology with varied clinical symptoms. Its pathogenesis is not exactly known and has a benign course. Here we present a case of a 42-year-old female with abnormal uterine bleeding who did not respond to medical management. On ultrasonography, suspected endometrial calcification was seen. Patient opted for hysterectomy and the biopsy report showed endometrial osseous metaplasia. Thus, in this case of menometrorrhagia and dysmenorrhoea, the cause was found to be osseous metaplasia.


Keywords


Dysmenorrhoea, Endometrial, Metaplasia, Menometrorrhagia, Osseous

Full Text:

PDF

References


Adamson NE, Sommers SC. Endometrial ossification: report of two cases. Am J Obstet Gynecol. 1954;67:187-90.

Umashankar T, Patted S, Handigund R. Endometrial osseous metaplasia: Clinicopathological study of a case and literature review. J Hum Reprod Sci. 2010;3:102-4.

Bhatia NN, Hoshiko MG. Uterine osseous metaplasia. Obstet Gynecol. 1982;60:256-9.

Bahçeci M, Demirel LC. Osseous metaplasia of the endometrium: a rare cause of infertility and its hysteroscopic management. Hum Reprod. 1996;11:2537-9.

Bedaiwy MA, Goldberg JM, Biscotti CV. Recurrent osseous metaplasia of the cervix after loop electrosurgical excision. Obstet Gynecol. 2001;98:968-70.

Campo S, Campo V, Zannoni GF, Gambadauro P. Simultaneous ovarian and endometrial osseous metaplasia: A case report. J Reprod Med. 2007;52:241-2.

Landim FM, Tavares JM, de Melo Braga DN, da Silva JE, Jr, Bastos Filho JB, Feitosa RG. Vaginal osseous metaplasia. Arch Gynecol Obstet. 2009;279:381-4

Shimizu M, Nakayama M. Endometrial ossification in a postmenopausal woman. J Clin Pathol. 1997;50:171-2.

Shroff CP, Kudterkar NG, Badhwar VR. Endometrial ossification- report of three cases with literature review. Indian J Pathol Microbiol. 1985;28:71-4.

Sugino N, Shimamura K, Takiguchi S, Tamura H, Ono M, Nakata M, et al. Changes in activity of superoxide dismutase in the human endometrium throughout the menstrual cycle and in early pregnancy. Hum Reprod. 1996;11:1073-8.

Lainas T, Zorzovilis I, Petsas G, Alexopoulou E, Lainas G, Ioakimidis T. Osseous metaplasia: case report and review. Fertil Steril. 2004;82:1433-5.

Madaan M, Suman S, Sharma R, Kapoor N, Garg P, Raj SS. Osseous metaplasia of the endometrium and successful hysteroscopic resection: report of two cases and a review of the literature. Asian J Endosc Surg. 2015;8(1):63-6.

Nicolae A, Preda O, Nogales FF. Endometrial metaplasias and reactive changes: a spectrum of altered differentiation. J Clin Pathol. 2011;64:97‑106.