A clinical study on peripartum cardiomyopathy at tertiary care hospital


  • Seeta S. Garag Department of Obstetrics and Gynecology, KIMS Hubali, Karnataka, India
  • Vinay Raju D. Department of Obstetrics and Gynecology, KIMS Hubali, Karnataka, India




Anemia, Cardiac diseases, Echocardiography, Maternal mortality, Peripartum cardiomyopathy, Pregnancy-induced hypertension


Background: Cardiac diseases complicate 1-4% of pregnancies in women without pre-existing cardiac abnormalities. Cardiac disease in the pregnant woman can present a challenge to the obstetrician, cardiologist and neonatologist. Peripartum cardiomyopathy (PPCM) is an idiopathic disorder defined as heart failure occurring in women during the last month of pregnancy and up to 5 months postpartum. Aim is to study the burden of the disease, maternal outcome in PPCM.

Methods: The present study was conducted among the antenatal women admitted in the department of Obstetrics and Gynecology at KIMS, Hubli with a previously diagnosed cardiac disease or diagnosed after admission during index pregnancy from December 2016 to May 2018. The mothers were followed up till discharge. Maternal outcome was noted as discharged or died.

Results: A total of 11 cases of PPCM noted in our study out of which one case was developed before delivery, and 10 cases developed postnatally. Out of ten cases which were developed postnatally, 5 patients died giving around 50% of mortality rate.

Conclusions: PPCM affects previously normal healthy women in the last month of pregnancy and up to 5 months after delivery. Careful assessment of risk factors contributing PPCM could help in their prevention. And these patients should be stratified in developing PPCM in future pregnancies through proper tools available.


Cunnigham FC, Leveno KJ, Bloom SJ, Hauth JC, Rouse DJ, Spong CY. Williams: obstetrics 24th edn. United States McGraw-Hill medical publishing division; 2014:973-1000.

Tomlinson MW. Chapter 36 Cardiac Disease: Editor: David K. James; High risk pregnancy: management options 4th ed; 2006;ISBN 978-1-4160-5908-0.

Pearson GD, Veille JC, Rahimtoola S, Hsia J, Oakley CM, Hosenpud JD, et al. Peripartum cardiomyopathy: national heart, lung, and blood institute and office of rare diseases (National Institutes of Health) workshop recommendations and review. JAMA. 2000;283(9):1183-8.

Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. Lancet. 2006;368(9536):687-69.

James P. A review of peripartum cardiomyopathy. Int J Clin Pract. 2004;58(4):363-5.

Karamitsos TD, Neubauer S. Detecting diffuse myocardial fibrosis with CMR: the future has only just begun. Cardiovascular Imaging; JACC. 2013;6(6):684-6.

Goland S, Modi K, Bitar F, Janmohamed M, Mirocha JM, Czer LSC, et al. Clinical profile and predictors of complications in peripartum cardiomyopathy. J Card Fail. 2009;15(8):645-50.

Sliwa K, Hilfiker-Kleiner D, Petrie MC. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy. Eu J Heart Fail. 2010;12(8):767-78.

Sovndal S, Tabas JA. Cardiovascular disorders in pregnancy. In: Pearlman MD, Tintinalli JE, Dyne PL, editors. Obstetric and Gynecologic Emergencies: Diagnosis and Management. 1st ed. New York: McGraw-Hill Medical Publishing Division; 2004:300-309.

Tidswell M. Peripartum cardiomyopathy. Crit Care Clin. 2004;20:777-88.

Bhattacharyya A, Basra SS, Sen P, Kar B. Peripartum cardiomyopathy: a review. Tex Heart Inst J. 2012;39(1):8-16.






Original Research Articles