A study on eclampsia and its maternal and perinatal outcome

Authors

  • Devika J. Kamat Department of Obstetrics and Gynecology, Goa Medical College, Bambolim, Goa, India
  • Guruprasad Pednecar Department of Obstetrics and Gynecology, Goa Medical College, Bambolim, Goa, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20195358

Keywords:

Eclampsia, Maternal and perinatal mortality

Abstract

Background: Eclampsia is one of the major causes of maternal and perinatal mortality in India. Here authors present a prospective study which was conducted in a tertiary health centre to study the cases of eclampsia, the mode of presentation and the maternal and perinatal outcomes.

Methods: A total 95 women were diagnosed as eclampsia during the period of 2 years. Various parameters and their effects on maternal and perinatal morbidity and mortality were studied. Maternal outcomes were assessed based on parameters like antenatal care received, mode of delivery, complications associated with eclampsia. Perinatal outcomes were noted depending upon the period of gestation, NICU admission, stillbirths and neonatal deaths.

Results: Authors found the incidence of eclampsia to be 0.9%. 52.7% women had irregular antenatal follow up at any nearby health centre. A total 76.8% women had antepartum eclampsia. 56.8% delivered by caesarean section while 7.4% required operative vaginal delivery. 61.1% women delivered within 10 hours of onset of convulsion. Authors had 02 deaths in the study group, one due to ARDS with DIC and the other attributed to pulmonary oedema. There were 51.6% preterm deliveries. 21 neonates required NICU admission with 5 neonatal deaths and 11 stillbirths.

Conclusions: Due to inadequate antenatal care, most of the cases of pre-eclampsia go unnoticed increasing the referrals to tertiary care centre for intensive care. Thus, it is necessary to emphasise on timely interventions and availability of blood bank, ICU and NICU facilities at the closest referral centre for better maternal and perinatal outcome.

References

Gifford RW, August PA, Cuuningham G, Green LA, Lindheimer M, McNellis D, et al. Working group of National High Blood Pressure Education Programme. NIH Publication No. 00-3029 revised; 2000:3-5.

World Health Organisation. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia 2011. Available at: http://whqlibdoc.who.int/publications/2011/9789241548335_eng.pdf. Accessed on 8th October 2019.

Patil MM. Role of neuroimaging in patients with atypical eclampsia. J Obstet Gynaecol India. 2012;62(5):526-30.

World Health Organisation. International Collaborative study of hypertensive disorders of pregnancy, geographic variation in the incidence of hypertension in pregnancy. Am J Obstet Gynaecol. 1988;158(1):80-3.

Sunitha TH, Dessai R. Eclampsia in a teaching hospital: incidence, clinical profile and response to magnesium sulphate by Zuspan’s regimen. IOSR-J Dent Med Sci. 2013;4(2):1-5.

Prabhakar G, Shinde MA, Jadhav CA. Clinical study of eclampsia at Dr. V. M. Government medical college Solapur, IOSR-JDMS. 2014;13(7):10-6.

Mor S, Daya S, Reetu H. Eclampsia: maternal and perinatal outcome in a tertiary care centre. In J Repro Contra Obstet Gynaecol. 2015;4(3):653-7.

Eckholm E, Salmi MM, Erkkola R. Eclampsia in Finland in 1990-1994. Acta obstetricia et gynaecologia Scandnavica. 1999;78(10):877-82.

Leitch R, Walker JJ. The changing pattern of eclampsia over a 60 year period. Br J Obstet Gynaecol. 1997;104:917-22.

Mahmoudi N, Graves SW, Solomon CG, Repke John T, Seely EW. Eclampsia: 13 year experiences at a United States Tertiary care center. J Women’s Health Gender-Based Med. 1999;8:495-500.

Tukur J, Umar BA, Rabiu A. Pattern of eclampsia in a tertiary health facility situated in a semi rural town in Northern Nigeria. Anna Af Med. 2007;6:164-7.

Akhtar R, Ferdous A, Syeda B. Maternal and fetal outcome of eclamptic patients in a tertiary hospital. Bangladesh J Obstet Gynaecol. 2011;26(2):77-80.

Shaheen B, Hassan L, Obaid M. Eclampsia: a major cause of maternal and perinatal mortality; a prospective analysis at a tertiary care hospital of Peshawar. J Peshawar Med Asso. 2003;53(8):346-50.

Sarma HK, Talukdar B. Eclampsia: a clinical prospective study in a referral hospital. J Obstet Gynaecol Barpeta. 2014;1(1):57-61t.

Edgar MN, Albert K, Richard R, Beatrice I, Anthony NM. Maternal and perinatal outcome among eclamptic patients admitted in Bugando Medical College, Mwanza, Tanzania. Af J Repro Health. 2012;16(1):35-41.

Vijayashree M, Murali GV. A clinical study of perinatal and maternal complications in eclampsia in a tertiary level referral centre - A near miss obstetric catastrophe. Int J Adv Multidi Res. 2015;2(4):80-5.

Choudhary P. Eclampsia: a hospital based retrospective study. Kathmandu Univ Med J. 2003;1(4):237-41.

Abdullah A, Shaikh AA, Jamro B. Maternal and perinatal outcome associated with eclampsia in a teaching hospital, Sukkur. Rawal Med J. 2010;35(1):23-6.

Douglas KA, Redman CW. Eclampsia in United Kingdom. Br Med J. 1994;309(6966):1395-400.

Asicioglu O, Gungorduk K, Yildirim G, Aslan H, Gunay T. Maternal and perinatal outcomes of eclampsia with or without HELLP syndrome in a teaching hospital in western Turkey. J Obstet Gynecol. 2014;34:326-31.

Anuja B, Sayali K, Sunita G, Anjali K, Sulabha J, Savita S. Eclampsia: maternal and fetal outcome. J South Asian Federat Obstet Gynecol. 2013;5(1):19-21.

Khan A, Arindam G, Banerjee PK, Tapan KM. Profile and outcome of eclampsia in a rural tertiary hospital. Int J Recent Trends Sci Tech. 2014;10(3):526-9.

Dhanajaya BS, Dayananda G, Sendilkumaran D, Murthy N. A study of factors affecting perinatal mortality in eclampsia. J Pharm Bioallied Sci. 2009;22(2):2-5.

Yaliwal RG, Jaju PB, Vanishree M. Eclampsia and perinatal outcome: a retrospective study in a teaching hospital. J Clin Diag Res. 2011;5(5):1056-59.

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Published

2019-11-26

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Original Research Articles