Published: 2019-12-26

Giant angioleiomyoma of uterus masquerading as ovarian tumour: a case report

Purnima Bhandari, Anil C. Humane, Vaishali S. Deshmukh


Angioleiomyoma is a rare benign tumour of uterus. We are presenting an unusual case of 45-year-old female with 11 kg giant angioleiomyoma of uterus which was masquerading as ovarian tumour on imaging. Exploratory laparotomy was done which was suggestive of huge lobulated mass arising from the uterus. Hysterectomy with bilateral salpingo-oophorectomy was done. Histopathological examination of specimen was suggestive of uterine subserosal and broad ligament angioleiomyoma of cavernous type. This case is being reported because of its rarity and challenges in diagnosis and management.


Angioleiomyoma, Giant, Masquerading, Ovarian tumour, Rare, Uterus

Full Text:



Weiss SW, Goldblum JR, editors. Benign tumors of smooth muscle. In: Enzinger and Weiss’s Soft Tissue Tumors. 4th. St. Louis, MO:The CV Mosby Co; 2001:699-700.

Garg G, Mohanty SK. Uterine angioleiomyoma: a rare variant of uterine leiomyoma. Arch Pathol Lab Med. 2014;138:1115-8.

Sharma C, Sharma M, Chander B, Soni A, Soni PK. Angioleiomyoma uterus in an adolescent girl: a highly unusual presentation. J Pediatr Adolesc Gynecol. 2014;27(3):e69-71.

Culhaci N, Ozkara E, Yüksel H, Ozsunar Y, Unal E. Spontaneously ruptured uterine angioleiomyoma. Pathol Oncol Res. 2006;12:50-1.

Handler M, Rezai F, Fless KG, Litinski M, Yodice PC. Uterine angioleiomyoma complicated by consumptive coagulopathy. Gynecol Oncol Case Rep. 2012;2(3):89-91.

Thomas S, Radhakrishnan L, Abraham L, Matthai A. Uterine angioleiomyoma with atypia, raised CA‑125 levels, and pseudo‑Meigs syndrome: an alarming presentation. Case Rep Pathol. 2012;2012:519473.

Hsieh CH, Lui CC, Huang SC, Ou YC, Chang Chien CC, Lan KC, et al. Multiple uterine angioleiomyomas in a woman presenting with severe menorrhagia. Gynecol Oncol. 2003;90:348-52.

Stewart EA, Nowak RA. Leiomyoma‑related bleeding: A classic hypothesis updated for the molecular era. Hum Reprod Update. 1996;2:295-306.

Hachisuga T, Hashimoto H, Enjoji M. Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer. 1984;54:126-30.

Zizi-Sermpetzoglou A, Myoteri D, Arkoumani E, Koulia K, Tsavari A, Alamanou E, et al. Angioleiomyoma of the uterus: report of a distinctive benign leiomyoma variant. Eur J Gynaecol Oncol. 2015;36:210-2.