DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20196050

First and second trimester bleeding and pregnancy outcome: a prospective study in a tertiary government hospital

Chaithra M., Anitha G. S., Sukanya Suresh, Savitha C.

Abstract


Background: Bleeding in first and second trimester of pregnancy is one of the common complications of pregnancy. there is evidence from various prospective and retrospective studies that first and second trimester vaginal bleeding which continue with pregnancy is associated with adverse pregnancy outcome, including preterm delivery, low birth weight babies, perinatal death and congenital anomalies. Objective of this study was to know the outcome of pregnancies who have bleeding in first and second trimester of pregnancy.

Methods: This study was prospective study done in the department of obstetrics and gynaecology, Vanivilas Hospital, Bangalore from September 2018 to August 2019.

Results: This study concludes that I trimester vaginal bleeding are at increased risk of abortion than in II trimester vaginal bleeding. Risk of placenta previa was more in II trimester vaginal bleeding than in I trimester vaginal bleeding.

Conclusions: This study concludes that I trimester vaginal bleeding are at increased risk of abortion than in II trimester vaginal bleeding. Risk of placenta previa was more in II trimester vaginal bleeding than in I trimester vaginal bleeding. Bleeding in I trimester and II trimester call for special attention in view of increased risk of preterm birth and perinatal death. Recognition of these association will be useful for detection and follow up of pregnancies being at high risk.


Keywords


Abortion, Perinatal outcome, Preterm delivery, Prelabor rupture of membranes, I and II trimester vaginal bleeding

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References


Strobino B, Pantel-Silverman JU. Gestational vaginal bleeding and pregnancy outcome. Am J Epidemiol. 1989;129:806-15.

Strobino B, Pantel-Silverman J. First trimester vaginal bleeding and the loss of chromosomally normal and abnormal conception. Am J Obstet Gynaecol. 1987;157:1150-4.

Berkowitz GS, Harlap S, Beck GJ, Freeman Dh, Baras M. Early gestational bleeding and pregnancy outcome: a multivariate analysis. Int J Epidemiol. 1983;12:16573.

Peckham CH. Uterine bleeding during pregnancy when not followed by immediate termination of pregnancy. Obstet Gynaecol. 1970;35:937-41.

South J, Neldert J. The effect of vaginal bleeding in early pregnancy on the infant born after the 28th week of pregnancy. J Obatet Gynecol. 1973;80:236-41.

Hertz JB, Heiaterberg L. The outcome of pregnancy after threatened abortion. Acta Obstet Gynecol Scand. 1985;64:151-6.

Evans JH, Beischer NA. The prognosis of threatened abortion. Med J Aust. 1970;2:165-8.

Funderburk SJ, Guthrie D, Meldrum D. Outcomes of pregnancies complicated by early vaginal bleeding. Br J Obstet Gynecol. 1980;87:100-5.

Batzofin TH, Fieding WL, Friedman AE. Effect of vaginal bleeding in early pregnancy outcome. Obstet Gynecol. 1984;63:515-8.

Axelsen SM, Henriksen TB, Hedegaard M, Secher NJ. Characteristics of vaginal bleeding during pregnancy. Eur J Obstet Gynecol Reprod Biol. 1995;63:131-4.

Yang J, Hartmann KE, Savitz DA, Herring AH, Dole N, Olshan AF, et al. Vaginal bleeding during pregnancy and preterm birth. Am J Epidemiol. 2004;160:118-25.

Elovitz MA, Baron J, Phillipe M. The role of thrombin in preterm parturition. AM J Obstet Gynecol. 2001;185:1059-63.

Rosen T, Kuczynski E, O'Neill LM, Funai EF, Lockwood CJ. Plasma levels of thrombin-antithrombin complexes predict preterm premature rupture of the fetal membranes. J Matern Fetal Med. 2001;10:297-300.

Karim SA, Bakhtawar I, Butta AT, Jalil M. Effects of first and second trimester vaginal bleeding on pregnancy outcome. J Pak Med Asso. 1998;48(2):40-2.

Amirkhani Z, Akhlaghdoust M, Abedian M, Salehi GR, Zarbati N, Mogharehabed M, et al. Maternal and perinatal outcomes in pregnant women with first trimester vaginal bleeding. J Family Reprod Health. 2013;7(2):57-61.

Kamble P, Bava A, Shukla M, Nandanvar Y. First trimester bleeding and pregnancy outcome. Int J Repro Contracept Obstet Gynecol. 2017;6(4):1484-7.