A rare case of toxic epidermal necrolysis in pregnancy

Authors

  • Reena Yadav Department of Obstetrics and Gynecology, Lady Hardinge Medical College and SSKH, New Delhi, India
  • Astha Srivastava Department of Obstetrics and Gynecology, Lady Hardinge Medical College and SSKH, New Delhi, India
  • Preeti Pawar Department of Obstetrics and Gynecology, Lady Hardinge Medical College and SSKH, New Delhi, India
  • Vibhu Mendiratta Department of Dermatology, Lady Hardinge Medical College and SSKH, New Delhi, India
  • Prerna Tayal Department of Obstetrics and Gynecology, Lady Hardinge Medical College and SSKH, New Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20200391

Keywords:

Pregnancy, Stevens-Johnson syndrome, Toxic epidermal necrolysis

Abstract

Stevens-Johnson syndrome (SJS) is a group of toxic necrolytic group of disorder of skin and mucous membrane with significant morbidity and mortality. It is a highly serious allergic reaction to medications affecting the skin and mucous membranes. Pregnant women with SJS or toxic epidermal necrolysis (TEN) are a unique subset, and both conditions can simultaneously affect the mother and fetus. It is a rare condition with a reported incidence of one case per million people per year. Till date, few cases of pregnancy with SJS/TEN have been reported. We are reporting a case of 20-year-old primigravida with 31+3 weeks of gestation presenting with extensive toxic epidermal necrosis. Attack of SJS developing in pregnancy can be fatal because immunity is compromised. This patient was managed in our institute with involvement of multidisciplinary team and had a successful pregnancy outcome. Perinatal outcome was also good in this case.

Author Biography

Astha Srivastava, Department of Obstetrics and Gynecology, Lady Hardinge Medical College and SSKH, New Delhi, India

References

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Published

2020-01-28

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Section

Case Reports