Transfusion practices in obstetrics and gynaecology in a tertiary care center

Shashi Singh, Parul Sinha, Gunjan Yadav, Uma Gupta, Priyanka Tyagi


Background: This study was an effort to identify and highlight existing transfusion practices in our hospital, including the indications of various blood components used and the allergic reaction encountered. Obstetric hemorrhage remains major cause of maternal mortality worldwide and Blood transfusion can be a lifesaving intervention.

Methods: This was a prospective cross- sectional study conducted on 172 patients who underwent blood and blood component transfusion. Hb concentration <7g/dL was determined to be an indication for blood product transfusion.

Results: In this study the most common indication for blood transfusion was antenatal patient with anemia (32.8%) followed by ruptured ectopic pregnancy (19.5%) and postpartum hemorrhage (18.8%). Amongst gynecological patients, the most common cause for transfusion was abnormal uterine bleeding (AUB) (61.4%). Majority patients were given single unit transfusion. Adverse reactions found in our study were not statistically significant.

Conclusions: Therefore this study concludes that we still need to go a long way in order to train the medical fraternity at all levels to learn to identify the valid indications for transfusion and select appropriate component for management.


Blood transfusion, Blood component therapy, Obstetric hemorrhage

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Ekeroma A, Ansari A, Stirrat G. Blood transfusion in obstetrics and gynecology. BJOG. 2005;104(3):278-84.

Gupte SC, Patel F, Patel P. Blood transfusion practice in obstetrics and gynecology. J Obstet Gynecol Ind. 2004;54(2):187-90.

David A. Sacks blood component replacement. Crit Care Obstetr. 5th edition. Hobken:NJ Wiley-Blackwell; 2010:165-180.

Deshpande S, Gadappa S, Yelikar K. Blood and blood components therapy in obstetrics and gynecology-a review. Indian J Res. 2014;3:(7).

Obaid TA. No woman should die giving life. Lancet. 2007;370:1287-8.

Saxtan J, Carnell S, Van Jaarsveld C, Wardle J. Maternal education is associated with feeding style. JAM Diet Assoc. 2009;109:894-8.

Oliveira M, Osorio M, Raposo M. Socioeconomic and dietary risk factors for anemia in children aged 6 to 59 months. J Pediatr (RioJ). 2007;83:39-46.

Vachhani JH, Joshi JR, Bhanvadia VM. Rational use of blood: a study report of single unit transfusion. Indian J Hematol Blood Transfus. 2008;24:69-71.

WHO Blood Safety Handbook (2001) the clinical use of blood. WHO/BTS/99.3,Geneva; 2001:122-34.

Gupte SC, Shaw A. Evaluation of single unit red cell transfusions given to adults during surgery. Asian J Transfus Sci. 2007;1:12-5.

Agarwal MB. Menorrhagia: haematologists point of view. Indian J Hematol Blood Transfus. 2003;21(2):29-33.

Mercier FJ, Bonnet MP. Use of clotting factors and other prohemostatic drugs for obstetric hemorrhage. Curr Opin Anaesthesiol. 2010;23:310-6.

Singi SR, Fernandez E, Pandya ST, Badrinath HR. Recombinant factor VIIa: use in fatal post-partum hemorrhage-Indian experience case series and review of literature. Indian J Hematol Blood Transfus. 2009;25:1-5.

Brecher ME. American association of blood banks. Technical manual. 15th edn. Bethesda, MD: AABB, 2005.

Simon TL, Alverson DC, AuBuchon J, Cooper ES, DeChristopher PJ, Glenn GC et al. Practice parameter for the use of red blood cell transfusions. Arch Pathol Lab Med. 1998;122:130-8.

Hofmeyr GJ, Mohala BKF. Hypovolemic shock. Best Pract Res Clin Obstet Gynaecol. 2001;15:645-62.